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On this plot, the slope is [– Km or: Vmaximum or Vmaximum" -] and the y-intercept is (-- or: Km or: V mazimum´ Ibuprofen [increases/decreases/does not change] Km and maximum (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.

On this plot, the slope is [– Km or: Vmaximum or Vmaximum" -] and the y-intercept is (-- or: Km or: V mazimum´ Ibuprofen [increases/decreases/does not change] Km and maximum (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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• Ibuprofen Ibuprolen 1/(S) Km On this plot, the slope is [-- -] and the y-intercept is Vmaximum" or or Vтaximum Km or Vmaximum 1 or Vmaximum Ibuprofen [increases/decreases/does not change] Km and Km (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.
Transcribed Image Text:• Ibuprofen Ibuprolen 1/(S) Km On this plot, the slope is [-- -] and the y-intercept is Vmaximum" or or Vтaximum Km or Vmaximum 1 or Vmaximum Ibuprofen [increases/decreases/does not change] Km and Km (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.
Expert Solution
Step 1

Lineweaver-Burk plot, also known as double-reciprocal plot, is the graph plotted for Lineweaver-Burk enzymatic kinetic equation. This equation is as follows:

1V0=KmVmax[S]+1Vmax

Where,

V0 is initial velocity

Km is Michaelis-Menten equation

Vmax is maximum velocity of reaction

[S] is substrate concentration

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