On this plot, the slope is [– Km or: Vmaximum or Vmaximum" -] and the y-intercept is (-- or: Km or: V mazimum´ Ibuprofen [increases/decreases/does not change] Km and maximum (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.
On this plot, the slope is [– Km or: Vmaximum or Vmaximum" -] and the y-intercept is (-- or: Km or: V mazimum´ Ibuprofen [increases/decreases/does not change] Km and maximum (increases/decreases/does not change] Vmax and is thus a [competitive/uncompetitive/noncompetitive] inhibitor of cyclooxygenase.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
Expert Solution
Step 1
Lineweaver-Burk plot, also known as double-reciprocal plot, is the graph plotted for Lineweaver-Burk enzymatic kinetic equation. This equation is as follows:
Where,
V0 is initial velocity
Km is Michaelis-Menten equation
Vmax is maximum velocity of reaction
[S] is substrate concentration
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