The drug UTSAone was investigated as a possible inhibitor of a dehydrogenase enzyme that acts on pregnenolone as a substrate in steroid synthesis. The activity of the dehydrogenase was measured in the presence and in the absence of 10 µM UTSAone.
The drug UTSAone was investigated as a possible inhibitor of a dehydrogenase enzyme that acts on pregnenolone as a substrate in steroid synthesis. The activity of the dehydrogenase was measured in the presence and in the absence of 10 µM UTSAone.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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a
The Km (uM) in the absence of UTSAone is 2.4.
The Km (uM) in the absence of UTSAone is 5.4
The Km (µM) in the presence of UTSAone is 2.4.
The Km (uM) in the presence of UTSAone is 5.3.
The Vmax (pmol/min) in the absence of UTSAone is 6.8 x 10-3.
e
The Vmax (pmol/min) in the presence of UTSAone is 5.0 x 10 3.
g
The x intercept (µM) in the absence of UTSAone is -0.186.
The x-intercept (µM) in the presence of UTSAone is -0.188.
UTSAone binds to a site other than the active site on the
i
dehydrogenase.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd5cc39c9-8b2b-4beb-a3cb-5d1bdcb587ab%2Fcbf3f450-d8ab-437b-adc2-3d482716bb11%2Fqttede_processed.jpeg&w=3840&q=75)
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a
The Km (uM) in the absence of UTSAone is 2.4.
The Km (uM) in the absence of UTSAone is 5.4
The Km (µM) in the presence of UTSAone is 2.4.
The Km (uM) in the presence of UTSAone is 5.3.
The Vmax (pmol/min) in the absence of UTSAone is 6.8 x 10-3.
e
The Vmax (pmol/min) in the presence of UTSAone is 5.0 x 10 3.
g
The x intercept (µM) in the absence of UTSAone is -0.186.
The x-intercept (µM) in the presence of UTSAone is -0.188.
UTSAone binds to a site other than the active site on the
i
dehydrogenase.
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Question 33
The drug UTSAone was investigated as a possible inhibitor of a dehydrogenase
enzyme that acts on pregnenolone as a substrate in steroid synthesis. The
activity of the dehydrogenase was measured in the presence and in the
absence of 10 uM UTSAone.
Which of the following statements are False?
(Pregnenolone, uM)
Vo without I (pmol/min)
Vo with I (pmol/min)
1.0
0.00106
0.00079
5.0
0.00327
0.00242
10.0
0.00439
0.00326
20.0
0.00529
0.00395
i) Multiple answers: Multiple answers are accepted for this question
Select one or more answers and submit. For keyboard navigation... SHOW MORE V
a
The Km (uM) in the absence of UTSAone is 2.4.
b
The Km (uM) in the absence of UTSAone is 5.4
The Km (uM) in the presence of UTSAone is 2.4.
d
The Km (uM) in the presence of UTSAone is 5.3.
The Vmax (pmol/min) in the absence of UTSAone is 6.8 x 10 3.
e](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd5cc39c9-8b2b-4beb-a3cb-5d1bdcb587ab%2Fcbf3f450-d8ab-437b-adc2-3d482716bb11%2Fha46w3_processed.jpeg&w=3840&q=75)
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Question 33
The drug UTSAone was investigated as a possible inhibitor of a dehydrogenase
enzyme that acts on pregnenolone as a substrate in steroid synthesis. The
activity of the dehydrogenase was measured in the presence and in the
absence of 10 uM UTSAone.
Which of the following statements are False?
(Pregnenolone, uM)
Vo without I (pmol/min)
Vo with I (pmol/min)
1.0
0.00106
0.00079
5.0
0.00327
0.00242
10.0
0.00439
0.00326
20.0
0.00529
0.00395
i) Multiple answers: Multiple answers are accepted for this question
Select one or more answers and submit. For keyboard navigation... SHOW MORE V
a
The Km (uM) in the absence of UTSAone is 2.4.
b
The Km (uM) in the absence of UTSAone is 5.4
The Km (uM) in the presence of UTSAone is 2.4.
d
The Km (uM) in the presence of UTSAone is 5.3.
The Vmax (pmol/min) in the absence of UTSAone is 6.8 x 10 3.
e
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