shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine; C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data i shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain you know this from the profiles? (B) Is this a problem for cough suppression? Explain.
shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine; C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data i shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain you know this from the profiles? (B) Is this a problem for cough suppression? Explain.
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
Related questions
Question
![The plasma profiles of codeine (COD) and metabolites for 2 individuals (labeled A and B) are
shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine;
C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data is
shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain how
you know this from the profiles? (B) Is this a problem for cough suppression? Explain.
-CH
HO
Codeine
COD
10 000
1000
C6G
COD
100
M3G
M6G
NM
10
M
10
20
30 0
10
20
30
Plasma concentration (nmol I-)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Febf69e27-3b27-4f98-a09a-8579a8586d1c%2F2ef8673f-eed0-4394-b6a2-a5d641285e5a%2Fr191zq_processed.png&w=3840&q=75)
Transcribed Image Text:The plasma profiles of codeine (COD) and metabolites for 2 individuals (labeled A and B) are
shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine;
C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data is
shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain how
you know this from the profiles? (B) Is this a problem for cough suppression? Explain.
-CH
HO
Codeine
COD
10 000
1000
C6G
COD
100
M3G
M6G
NM
10
M
10
20
30 0
10
20
30
Plasma concentration (nmol I-)
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