knowledge of the kinetic properties of competitive, uncompetitive and mixed inhibitors, determine the nature of the inhibition by Astrozolamide and explain your reasoning! 100 No inhibitor Astrozolamide 0.2 0.4 0.6 0.8 (S) (mm) pre"A JO %) A
knowledge of the kinetic properties of competitive, uncompetitive and mixed inhibitors, determine the nature of the inhibition by Astrozolamide and explain your reasoning! 100 No inhibitor Astrozolamide 0.2 0.4 0.6 0.8 (S) (mm) pre"A JO %) A
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
![15. Dodgerase is an enzyme that is exquisitely inhibited by a class of cheaters
(Astrozolamide and Redsoxin). Dodgerase plays an important role in the civic pride of
one of the greatest and most diverse cities in the world. The experimental curve of
initial reaction velocity (as percentage of Vmax) versus [S] for the Dodgerase reaction is
shown (upper curve). When the experiment was run in 2017, in the presence of
inhibitor, the lower curve was obtained. From an inspection of the curves and your
knowledge of the kinetic properties of competitive, uncompetitive and mixed inhibitors,
determine the nature of the inhibition by Astrozolamide and explain your reasoning!
100
No inhibitor
50
Astrozolamide
0.2
0.4
0.6
0.8
[S] (mm)
pee"A JO %) A](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F0ebba35e-af4d-4762-b8f9-1381a8fd7b7a%2Feb2a41b8-5880-4bae-b255-2225a13d25ef%2Fpymghr_processed.jpeg&w=3840&q=75)
Transcribed Image Text:15. Dodgerase is an enzyme that is exquisitely inhibited by a class of cheaters
(Astrozolamide and Redsoxin). Dodgerase plays an important role in the civic pride of
one of the greatest and most diverse cities in the world. The experimental curve of
initial reaction velocity (as percentage of Vmax) versus [S] for the Dodgerase reaction is
shown (upper curve). When the experiment was run in 2017, in the presence of
inhibitor, the lower curve was obtained. From an inspection of the curves and your
knowledge of the kinetic properties of competitive, uncompetitive and mixed inhibitors,
determine the nature of the inhibition by Astrozolamide and explain your reasoning!
100
No inhibitor
50
Astrozolamide
0.2
0.4
0.6
0.8
[S] (mm)
pee"A JO %) A
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