6. Noncompetitive inhibition is a limiting case in which the effect of binding inhibitóf has no effect on the affinity for the substrate and vice versa. Suggest what a Lineweaver- Burk plot would look like for an inhibitor that had a reaction scheme similar to the scheme below, but where binding inhibitor lowered the affinity of EI for the substrate.
6. Noncompetitive inhibition is a limiting case in which the effect of binding inhibitóf has no effect on the affinity for the substrate and vice versa. Suggest what a Lineweaver- Burk plot would look like for an inhibitor that had a reaction scheme similar to the scheme below, but where binding inhibitor lowered the affinity of EI for the substrate.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Number 6 please
![0. Noncompetitive inhibition is a limiting case in which the effect of binding inhibitor has
no effect on the affinity for the substrate and vice versa. Suggest what a Lineweaver–
Burk plot would look like for an inhibitor that had a reaction scheme similar to the
scheme below, but where binding inhibitor lowered the affinity of EI for the substrate.
Slope=
Van
(1+)
EI
-1
Slope
Veax
ES
ESI
KM
V
(S]
Page 7 of 10](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F36694eb9-7df5-4471-b965-26275952eee1%2F0c2624b8-6ba1-4bea-9fb3-ada012a969bb%2F57zfc78_processed.jpeg&w=3840&q=75)
Transcribed Image Text:0. Noncompetitive inhibition is a limiting case in which the effect of binding inhibitor has
no effect on the affinity for the substrate and vice versa. Suggest what a Lineweaver–
Burk plot would look like for an inhibitor that had a reaction scheme similar to the
scheme below, but where binding inhibitor lowered the affinity of EI for the substrate.
Slope=
Van
(1+)
EI
-1
Slope
Veax
ES
ESI
KM
V
(S]
Page 7 of 10
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