How to calculate glomerular filtration rate given this information: molecular weight of drug, total plasma concentration, and percent of drug that is protein plasma bound?
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How to calculate glomerular filtration rate given this information: molecular weight of drug, total plasma concentration, and percent of drug that is protein plasma bound?
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- What concentration of sucrose do you estimate would yield no change inpressure? Why is this biologically significant? Explain in your own words. Do not copy and paste from google. Please refer to your data/graphs on Dialysis tubing cell osmosis.One model of the glomerular membrane is a microporous membrane in which right cylindrical pores penetrate all the way through the membrane. Assume that the pores have a length of 50 nm and a radius of 3.5 nm. The viscosity of plasma is 0.002 Pa s. The average hydrostatic pressure in the glomerulus is 60 mm Hg, hydrostatic pressure in Bowman's space is 20 mm Hg and the average oncotic pressure of glomerular capillary blood is 28 mm Hg. A. Calculate the flow through a single pore assuming laminar flow (use the Poiseuille flow equation) B. How many pores would there have to be to produce a normal GFR? C. If the total aggregate area of the kidneys for filtration is 1.5 m2, what is the density of the pores (number of pores per unit area)? D. What fraction of the area is present as pores?The normal glomerular filtration rate in the following results is: 1) 2 ml/min, 2) 125 ml/min 3) 800 ml/min 4) 1,200 ml/min
- Calculate net filtration pressure given the following values: glomerular hydrostatic pressure = 50 mm Hg, blood colloid osmotic pressure = 25 mm Hg, capsular hydrostatic pressure = 20 Hg.Table 3. Serum creatinine values at admission and after 12h Admission +12h SCR(mg/dL) 1.55 1.42 Using the “MDRD” (Modification of Diet in Renal Disease) equation for estimating glomerularfiltration, provided below, and the data available in the above table, calculate the patient's (a 34 year old white male) estimated glomerularfiltration rate (eGFR) at admission and 12h after admission.MDRD GFR Equation (mL/min/1.73 m2)= 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American)Based on your calculated values, state whether LF’s function is normal or abnormal?Previous research suggests that patients with asthma have an increased risk for chronic kidneydisease, but the mechanisms underlying this increased risk are poorly understood. Propose one potential mechanism by which asthma might impair kidney function, and discuss how this dysfunction may impair thebody’s ability to respond to respiratory alkalosisthe major difference between plasma and interstitial fluid is the absence of plasma proteins from the interstitial. explain how this affects solute distrbution and what kind of correction you would do it if you were measuring solute concentration
- What is the patient's creatinine clearance given the following data? Serum creatinine 0.6 mg/dL Urine creatinine 102 mg/dL 24 hr urine volume 1650 mL Patient's BSA 1.93 m2 1) 195 mL/min 2) 130 mg/dL 3) 93 mL/min 4) 175 mL/min no references, just homework30, With respect to renal autoregulation, myogenic mechanism refers to Multiple Choice both glomerulus increase of blood flow and macula densa secreting renin are correct ability of macula densa to sense a increase in Na+ content in tubular fluid and secrete renin in response ability of a muscle to contract reflexively without nervous stimulation to adjust blood vessel diameter ability of glomerulus to increase blood flow and increase filtration rateThe set of results that most accurately reflects severe renal disease is: 1) Serum creatinine, 1.0mg/dL;creatinine clearance, 110 ml/min; BUN, 17mg/dL 2) Serum creatinine, 1.0mg/dL; creatinine clearance, 95 ml/min; BUN, 43 mg/dL 3) Serum creatinine, 2.0mg/dL; creatinine clearance, 120 ml/min; BUN, 14 mg/dL 4) Serum creatinine, 3.7 mg/dL; creatinine clearance, 44 ml/min; BUN, 88 mg/dL
- Construct a graph showing difusión time vs column height: don't forget to label axis. Consider how big is my graph.A creatinine clearance is done on a patient with the following results: serum creatinine, 0.6 mg/dL; urine creatinine, 102 mg/dL; urine volume, 1650 mL/24 hours; body surface area, 1.93 m2. Based on the information from calculations above, which of the following is the best interpretation of this patient's creatinine clearance results? 1) Within the normal range 2) Above normal, probably because the 24-hr urine collection was not completed correctly 3) Above normal 4) Below normal no references, just homeworkAfferent Arteriole Efferent Arteriole G F A E B D C 4.04 Tubular Reabsorption and Secretion Abbygail is a 50-year-old woman who is being seen in her doctor's office. Her chief complaint is that she has noticed that her urine has a darker color than her usual, yellow-colored urine. The doctor has a urinalysis test performed and it shows a moderate amount of protein in her urine. Explain what structure of the nephron is not working properly (causing the protein to be present in her urine). Be sure to identify the name of the structure that is likely to be involved and the letter in the diagram below that points to this structure. Remember to provide evidence to support your claim, along with a reasoning statement that ties your evidence and details to your claim.
