construct! Which of the four constructs (Construct 1-4) below could you use to make your own mouse knockout? For each one you did not choose, explain why you did not choose that construct. Part of DHCR7 gene structure is shown on top row in the schematic. (Antibiotic selection and negative selection genes have been abbreviated.)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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construct! Which of the four constructs
(Construct 1-4) below could you use to make
your own mouse knockout? For each one
you did not choose, explain why you did not
choose that construct. Part of DHCR7 gene
structure is shown on top row in the
schematic. (Antibiotic selection and negative
selection genes have been abbreviated.)
Gene DHCR7
Intron 1
Exon 2
Intron 2
Exon 3
Exon1
Construct #1
Construct #2
Intron1 Negative Sel.
Intron1
|Antibio. Sel. Negative Sel.
Intron2
Antibio. Sel
Intron 2
Construct #3
Construct #4
Introni Antibio. Sel Negative Sel.
Negative Sel.
Antibio. Sel.
Intron2
Intron1
Intron2
Transcribed Image Text:construct! Which of the four constructs (Construct 1-4) below could you use to make your own mouse knockout? For each one you did not choose, explain why you did not choose that construct. Part of DHCR7 gene structure is shown on top row in the schematic. (Antibiotic selection and negative selection genes have been abbreviated.) Gene DHCR7 Intron 1 Exon 2 Intron 2 Exon 3 Exon1 Construct #1 Construct #2 Intron1 Negative Sel. Intron1 |Antibio. Sel. Negative Sel. Intron2 Antibio. Sel Intron 2 Construct #3 Construct #4 Introni Antibio. Sel Negative Sel. Negative Sel. Antibio. Sel. Intron2 Intron1 Intron2
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