Consider the mRNA sequence below. Assume that the following mRNA segment has been translated. 5'-UUCCCAAAGUAU-3' Note for numbers 1 and 2: Use the three-letter abbreviation of amino acid; separate amino acids with a hyphen: do not include the stop codon. Example: ala-cys-glu 1. Using the table of the genetic code, determine the sequence of amino acids. 2. If mutation occurs by substitution of the 12th nucleotide with cytidine-5'- monophosphate, what is the resulting amino acid sequence? 3. What type of mutation occurred? Choose from same sense, missense and nonsense.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 16QP: Given the following tRNA anticodon sequence, derive the mRNA and the DNA template strand. Also,...
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first base
A
G
UUU
UUC
} phe
UUG}
leu
CUU
leu
CUC
CUA
CUG
AUU
AUC
AUA
{}
ile
AUG met (start)
GUU
GUC
val
GUA
GUG
UCU
UCC
UCA
UCG
CCU
CCC
CCA
CCG
ACU
ACC
ACA
ACG
GCU
GCC
GCA
GCG
C
second base
UAU
UAC
}
tyr
UAA Stop
UAG Stop
CAC} his
CAA
CAG
}gin
AAU
asn
AAC
AAA
AAG
lys
GAC
asp
GAA
}
GAG glu
ser
pro
thr
ala
}
G
UGC} cys
UGA Stop
UGG trp
CGU
CGC
CGA
arg
CGG
ser
AGC}
AGA
AGG
arg
GGU
GGC
gly
GGA
GGG
DOAG
A
U
CAG
third base
Transcribed Image Text:first base A G UUU UUC } phe UUG} leu CUU leu CUC CUA CUG AUU AUC AUA {} ile AUG met (start) GUU GUC val GUA GUG UCU UCC UCA UCG CCU CCC CCA CCG ACU ACC ACA ACG GCU GCC GCA GCG C second base UAU UAC } tyr UAA Stop UAG Stop CAC} his CAA CAG }gin AAU asn AAC AAA AAG lys GAC asp GAA } GAG glu ser pro thr ala } G UGC} cys UGA Stop UGG trp CGU CGC CGA arg CGG ser AGC} AGA AGG arg GGU GGC gly GGA GGG DOAG A U CAG third base
Consider the mRNA sequence below. Assume that the following mRNA segment has been translated.
5¹-UUCCCAAAGUAU-3'
Note for numbers 1 and 2: Use the three-letter abbreviation of amino acid; separate amino acids with a
hyphen: do not include the stop codon.
Example: ala-cys-glu
1. Using the table of the genetic code, determine the sequence of amino acids.
2. If mutation occurs by substitution of the 12th nucleotide with cytidine-5'- monophosphate, what is the
resulting amino acid sequence?
3. What type of mutation occurred? Choose from same sense, missense and nonsense.
Transcribed Image Text:Consider the mRNA sequence below. Assume that the following mRNA segment has been translated. 5¹-UUCCCAAAGUAU-3' Note for numbers 1 and 2: Use the three-letter abbreviation of amino acid; separate amino acids with a hyphen: do not include the stop codon. Example: ala-cys-glu 1. Using the table of the genetic code, determine the sequence of amino acids. 2. If mutation occurs by substitution of the 12th nucleotide with cytidine-5'- monophosphate, what is the resulting amino acid sequence? 3. What type of mutation occurred? Choose from same sense, missense and nonsense.
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