An mRNA transcript has the following complete sequence: 5'-AUGCCUACGUUACGGACC-3' Rewrite the sequence to give it a missense mutation. Circle/highlight the mutation. Explain how your specific mutation would affect the formation and structure of the 2nd (middle) Base of a Codon 1st U C A G 3rd Base Base UUU Phe UUC Phe UUA Leu UUG Leu UCU Phe UCC Phe UCA Leu UCG Leu UAU Tyr UAC Tyr UAA STOP UAG STOP UGU Cys UGC Oys UGA STOP UGG Trp protein. U CCU Pro CCC Pro CCA Pro CCG Pro CGU CUU Leu CUC Leu CUA Leu CUG Leu CAU His CAC His CAA Gin CAG Gin C CGG Arg AUU lle AUC lle AUA lle AUG Met ACU Thr ACC Thr ACA Thr ACG Thr AAU Asn AAC Asn AAA Lys AAG Lys AGU Ser AGC Ser AGA Arg AGG Arg A GAU Asp GAC Asp GAA Glu GAG Glu GGU Gly GGC Gly GGA Gly GGG Gy GCU Ala GCC Ala GUU Val GUC Val GUA Val GUG Vel G GCA Ala GCG Ala POAG

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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An mRNA transcript has the following complete sequence: 5'-AUGCCUACGUUACGGACC-3'
Rewrite the sequence to give it a
missense mutation. Circle/highlight
the mutation. Explain how your
specific mutation would affect the
formation and structure of the
2nd (middle) Base of a Codon
1st
U
CA
G
3rd
Base
Base
UUU Phe
UUC Phe
UUA Leu
UUG Leu
UCU Phe
UCC Phe
UCA Leu
UCG Leu
UAU Tyr
UAC Tyr
UAA STOP
UAG STOP
UGU Cys
UGC Cys
UGA STOP
UGG Trp
protein.
U
CUU Leu
CUC Leu
CUA Leu
CUG Leu
CCU Pro
ССС Pro
CCA Pro
CCG Pro
CAU His
CAC His
CAA Gln
CAG Gln
CGU Arg
CGC Arg
CGA Arg
CGG Arg
AGU Ser
AGC Ser
AGA Arg
AGG Arg
AAU Asn
AAC Asn
AUU lle
AUC lle
AUA lle
AUG Met
ACU Thr
ACC Thr
ACA Thr
ACG Thr
A
AAA Lys
AAG Lys
GUU Val
GUC Val
GUA Val
GUG Val
GCU Ala
GCC Ala
GCA Ala
GCG Ala
GAU Asp
GAC Asp
GAA Glu
GAG Glu
GGU Gly
GGC Gly
GGA Gly
GGG Gly
UCAG
Transcribed Image Text:An mRNA transcript has the following complete sequence: 5'-AUGCCUACGUUACGGACC-3' Rewrite the sequence to give it a missense mutation. Circle/highlight the mutation. Explain how your specific mutation would affect the formation and structure of the 2nd (middle) Base of a Codon 1st U CA G 3rd Base Base UUU Phe UUC Phe UUA Leu UUG Leu UCU Phe UCC Phe UCA Leu UCG Leu UAU Tyr UAC Tyr UAA STOP UAG STOP UGU Cys UGC Cys UGA STOP UGG Trp protein. U CUU Leu CUC Leu CUA Leu CUG Leu CCU Pro ССС Pro CCA Pro CCG Pro CAU His CAC His CAA Gln CAG Gln CGU Arg CGC Arg CGA Arg CGG Arg AGU Ser AGC Ser AGA Arg AGG Arg AAU Asn AAC Asn AUU lle AUC lle AUA lle AUG Met ACU Thr ACC Thr ACA Thr ACG Thr A AAA Lys AAG Lys GUU Val GUC Val GUA Val GUG Val GCU Ala GCC Ala GCA Ala GCG Ala GAU Asp GAC Asp GAA Glu GAG Glu GGU Gly GGC Gly GGA Gly GGG Gly UCAG
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