10. Glycine has 2 ionizable functional groups. Write the equilibrium equations for its three ionizations, and assign the proper pKa (2.34, 9.60) for each ionization. Draw the structure of Glycine in three ionization states. Indicate the net charge on the Glycine molecule in each ionization state. Structure Net charge a. COO- H3N-C-H H Please calculate the isoelectric point of Glycine. b. Draw the structures of the predominant ionization state of Glycine at pH 1 and 14.
10. Glycine has 2 ionizable functional groups. Write the equilibrium equations for its three ionizations, and assign the proper pKa (2.34, 9.60) for each ionization. Draw the structure of Glycine in three ionization states. Indicate the net charge on the Glycine molecule in each ionization state. Structure Net charge a. COO- H3N-C-H H Please calculate the isoelectric point of Glycine. b. Draw the structures of the predominant ionization state of Glycine at pH 1 and 14.
Basic Clinical Laboratory Techniques 6E
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ISBN:9781133893943
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Chapter6: Basic Clinical Chemistry
Section6.1: Introduction To Clinical Chemistry
Problem 12RQ
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
Transcribed Image Text:10. Glycine has 2 ionizable functional groups. Write the equilibrium equations for its three
ionizations, and assign the proper pKa (2.34, 9.60) for each ionization. Draw the structure of
Glycine in three ionization states. Indicate the net charge on the Glycine molecule in each
ionization state.
Structure
Net charge
a.
COO-
H3N-C-H
H
Please calculate the isoelectric point of Glycine.
b. Draw the structures of the predominant ionization state of Glycine at pH 1 and 14.
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