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OH (2-trans, 6-trans)-Farnesol Farnesol 2-isomerase (2-cis, 6-trans)-Farnesol OH

OH (2-trans, 6-trans)-Farnesol Farnesol 2-isomerase (2-cis, 6-trans)-Farnesol OH

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The reversible isomerization of (2-trans,6-trans)-farnesol into (2-cis,6-trans)-farnesol is catalyzed by the enzyme farnesol 2-isomerase.

You make a solution containing 100mM (2-trans,6-trans)-farnesol and leave the solution at room temperature (22oC). After 24 hours, the concentrations of (2-trans,6-trans)-farnesol and (2-cis,6-trans)-farnesol have not changed. Which of the following interventions is most likely to lead to a measurable increase in the formation of (2-cis,6-trans)-farnesol from (2-trans,6-trans)-farnesol?

  1. increasing the temperature of the solution to body temperature (~37oC)
  2. decreasing the temperature of the solution to nearly freezing (~4oC)
  3. increasing the concentration of (2-trans,6-trans)-farnesol
  4. addition of (2-cis,6-trans)-farnesol
  5. addition of farnesol 2-isomerase
OH (2-trans, 6-trans)-Farnesol Farnesol 2-isomerase (2-cis, 6-trans)-Farnesol OH
Transcribed Image Text:OH (2-trans, 6-trans)-Farnesol Farnesol 2-isomerase (2-cis, 6-trans)-Farnesol OH
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