Genetics: A Conceptual Approach6th EditionBenjamin A. Pierce Publisher: W. H. FreemanISBN: 9781319050962
Genetics: A Conceptual Approach
Browse All Chapters of This Textbook
Chapter 1 - Introduction To GeneticsChapter 1.1 - Genetics Is Important To Us Individually, To Society, And To The Study Of BiologyChapter 1.2 - Humans Have Been Using Genetic Techniques For Thousands Of YearsChapter 1.3 - A Few Fundamental Concepts Are Important For The Start Of Our Journey Into GeneticsChapter 2 - Chromosomes And Cellular ReproductionChapter 2.1 - Prokaryotic And Eukaryotic Cells Differ In A Number Of Genetic CharacteristicsChapter 2.2 - Cell Reproduction Requires The Copying Of The Genetic Material, Separation Of The Copies, And Cell DivisionChapter 2.3 - Sexual Reproduction Produces Genetic Variation Through The Process Of MeiosisChapter 3 - Basic Principles Of HeredityChapter 3.1 - Gregor Mendel Discovered The Basic Principles Of Heredity
Chapter 3.2 - Monohybrid Crosses Reveal The Principle Of Segregation And The Concept Of DominanceChapter 3.3 - Dihybrid Crosses Reveal The Principle Of Independent AssortmentChapter 3.4 - Observed Ratios Of Progeny May Deviate From Expected Ratios By ChanceChapter 4 - Sex Determination And Sex-linked CharacteristicsChapter 4.1 - Sex Is Determined By A Number Of Different MechanismsChapter 4.2 - Sex-linked Characteristics Are Determined By Genes On The Sex ChromosomesChapter 4.3 - Dosage Compensation Equalizes The Amount Of Protein Produced By X-linked And Autosomal Genes In Some AnimalsChapter 5 - Extensions And Modifications Of Basic PrinciplesChapter 5.1 - Additional Factors At A Single Locus Can Affect The Results Of Genetic CrossesChapter 5.2 - Gene Interaction Takes Place When Genes At Multiple Loci Determine A Single PhenotypeChapter 5.3 - Sex Influences The Inheritance And Expression Of Genes In A Variety Of WaysChapter 5.4 - Anticipation Is The Stronger Or Earlier Expression Of Traits In Succeeding GenerationsChapter 5.5 - The Expression Of A Genotype May Be Influenced By Environmental EffectsChapter 6.1 - The Study Of Genetics In Humans Is Constrained By Special Features Of Human Biology And CultureChapter 6.2 - Geneticists Often Use Pedigrees To Study The Inheritance Of Characteristics In HumansChapter 6.3 - Studying Twins And Adoptions Can Help Us Assess The Importance Of Genes And EnvironmentChapter 6.4 - Genetic Counseling And Genetic Testing Provide Information To Those Concerned About Genetics Diseases And TraitsChapter 7 - Linkage, Recombination, And Eukaryotic Gene MappingChapter 7.1 - Linked Genes Do Not Assort IndependentlyChapter 7.2 - Linked Genes Segregate Together While Crossing Over Produces Recombination Between ThemChapter 7.3 - A Three-point Testcross Can Be Used To Map Three Linked GenesChapter 7.4 - Physical-mapping Methods Are Used To Determine The Physical Positions Of Genes On Particular ChromosomesChapter 7.5 - Recombination Rates Exhibit Extensive VariationChapter 8.1 - Chromosome Mutations Include Rearrangements, Aneuploidy, And PolyploidyChapter 8.2 - Chromosome Rearrangements Alter Chromosome StructureChapter 8.3 - Aneuploidy Is An Increase Or Decrease In The Number Of Individual ChromosomesChapter 8.4 - Polyploidy Is The Presence Of More Than Two Sets Of ChromosomesChapter 9.1 - Bacteria And Viruses Have Important Roles In Human Society And The World EcosystemChapter 9.2 - Genetic Analysis Of Bacteria Requires Special MethodsChapter 9.3 - Bacteria Exchange Genes Through Conjugation, Transformation, And TransductionChapter 9.4 - Viruses Are Simple Replicating Systems Amenable To Genetic AnalysisChapter 10 - Dna: The Chemical Nature Of The GeneChapter 10.1 - Genetic Material Possesses Several Key CharacteristicsChapter 10.2 - All Genetic Information Is Encoded In The Structure Of Dna Or RnaChapter 10.3 - Dna Consists Of Two Complementary And Antiparallel Nucleotide Strands That Form A Double HelixChapter 10.4 - Special Structures Can Form In Dna And RnaChapter 11 - Chromosome Structure And Organelle DnaChapter 11.1 - Large Amounts Of Dna Are Packed Into A CellChapter 11.2 - Eukaryotic Chromosomes Possess Centromeres And TelomeresChapter 11.3 - Eukaryotic Dna Contains Several Classes Of Sequence VariationChapter 11.4 - Organelle Dna Has Unique CharacteristicsChapter 12.1 - Genetic Information Must Be Accurately Copied Every Time A Cell DividesChapter 12.2 - All Dna Replication Takes Place In A Semiconservative MannerChapter 12.3 - Bacterial Replication Requires A Large Number Of Enzymes And ProteinsChapter 12.4 - Eukaryotic Dna Replication Is Similar To Bacterial Replication But Differs In Several AspectsChapter 12.5 - Recombination Takes Place Through The Alignment, Breakage, And Repair Of Dna StrandsChapter 13 - TranscriptionChapter 13.1 - Rna, Consisting Of A Single Strand Of Ribonucleotides, Participates In A Variety Of Cellular FunctionsChapter 13.2 - Transcription Is The Synthesis Of An Rna Molecule From A Dna TemplateChapter 13.3 - Bacterial Transcription Consists Of Initiation, Elongation, And TerminationChapter 13.4 - Eukaryotic Transcription Is Similar To Bacterial Transcription But Has Some Important DifferencesChapter 14.1 - Many Genes Have Complex StructuresChapter 14.2 - Messenger Rnas, Which Encode Proteins, Are Modified After Transcription In EukaryotesChapter 14.3 - Transfer Rnas, Which Attach To Amino Acids, Are Modified After Transcription In Bacterial And Eukaryotic CellsChapter 14.4 - Ribosomal Rna, A Component Of The Ribosome, Is Also Processed After TranscriptionChapter 14.5 - Small Rna Molecules Participate In A Variety Of FunctionsChapter 15.1 - Many Genes Encode ProteinsChapter 15.2 - The Genetic Code Determines How The Nucleotide Sequence Specifies The Amino Acid Sequence Of A ProteinChapter 15.3 - Amino Acids Are Assembled Into A Protein Through TranslationChapter 15.4 - Additional Properties Of Rna And Ribosomes Affect Protein SynthesisChapter 16 - Control Of Gene Expression In BacteriaChapter 16.1 - The Regulation Of Gene Expression Is Critical For All OrganismsChapter 16.2 - Operons Control Transcription In Bacterial CellsChapter 16.3 - Some Operons Regulate Transcription Through Attenuation, The Premature Termination Of TranscriptionChapter 16.4 - Other Sequences Control The Expression Of Some Bacterial GenesChapter 17 - Control Of Gene Expression In EukaryotesChapter 17.1 - Eukaryotic Cells And Bacteria Share Many Features Of Gene Regulation But Differ In Several Important WaysChapter 17.2 - Changes In Chromatin Structure Affect The Expression Of Eukaryotic GenesChapter 17.3 - The Initiation Of Transcription Is Regulated By Transcription Factors And Transcriptional Regular ProteinsChapter 17.4 - Some Eukaryotic Genes Are Regulated By Rna Processing And DegradationChapter 17.5 - Rna Interference Is An Important Mechanism Of Gene RegulationChapter 17.6 - The Expression Of Some Genes Is Regulated By Processes That Affect Translation Or By Modification Of ProteinsChapter 18.1 - Mutations Are Inherited Alterations In The Dna SequenceChapter 18.2 - Mutations May Be Caused By A Number Of Different FactorsChapter 18.3 - Mutations Are The Focus Of Intense Study By GeneticistsChapter 18.4 - Transposable Elements Can Cause MutationsChapter 18.5 - A Number Of Pathways Can Repair DnaChapter 19.1 - Genetics Has Been Transformed By The Development Of Molecular TechniquesChapter 19.2 - Molecular Techniques Are Used To Cut And Visualize Dna SequencesChapter 19.3 - Specific Dna Fragments Can Be AmplifiedChapter 19.4 - Molecular Techniques Can Be Used To Find Genes Of InterestChapter 19.5 - Dna Sequences Can Be Determined And AnalyzedChapter 19.6 - Molecular Techniques Are Increasingly Used To Analyze Gene FunctionChapter 19.7 - Biotechnology Harnesses The Power Of Molecular GeneticsChapter 20.1 - Structural Genomics Determines The Dna Sequences And Organization Of Entire GenomesChapter 20.2 - Functional Genomics Determines The Functions Of Genes By Using Genomic ApproachesChapter 20.3 - Comparative Genomics Studies How Genomes EvolveChapter 20.4 - Proteomics Analyzes The Complete Set Of Proteins Found In A CellChapter 21 - EpigeneticsChapter 21.1 - What Is Epigenetics?Chapter 21.2 - Several Molecular Processes Lead To Epigenetic ChangesChapter 21.3 - Epigenetic Processes Produce A Diverse Set Of EffectsChapter 21.4 - The EpigenomeChapter 22.1 - Development Takes Place Through Cell DeterminationChapter 22.2 - Pattern Formation In Drosophila Serves As A Model For The Genetic Control Of DevelopmentChapter 22.3 - Genes Control The Development Of Flowers In PlantsChapter 22.4 - Programmed Cell Death Is An Integral Part Of DevelopmentChapter 22.5 - The Study Of Development Reveals Patterns And Processes Of EvolutionChapter 22.6 - The Development Of Immunity Occurs Through Genetic RearrangementChapter 23 - Cancer GeneticsChapter 23.1 - Cancer Is A Group Of Diseases Characterized By Cell ProliferationChapter 23.2 - Mutations In Several Types Of Genes Contribute To CancerChapter 23.3 - Epigenetic Changes Are Often Associated With CancerChapter 23.4 - Colorectal Cancer Arises Through The Sequential Mutation Of A Number Of GenesChapter 23.5 - Changes In Chromosome Number And Structure Are Often Associated With CancerChapter 23.6 - Viruses Are Associated With Some CancersChapter 24.1 - Quantitative Characteristics Are Influenced By Alleles At Multiple LociChapter 24.2 - Statistical Methods Are Required For Analyzing Quantitative CharacteristicsChapter 24.3 - Heritability Is Used To Estimate The Proportion Of Variation In A Trait That Is GeneticChapter 24.4 - Genetically Variable Traits Change In Response To SelectionChapter 25.1 - Genotypic And Allelic Frequencies Are Used To Describe The Gene Pool Of A PopulationChapter 25.2 - The Hardy–weinberg Law Describes The Effect Of Reproduction On Genotypic And Allelic FrequenciesChapter 25.3 - Nonrandom Mating Affects The Genotypic Frequencies Of A PopulationChapter 25.4 - Several Evolutionary Forces Can Change Allelic FrequenciesChapter 26.1 - Evolution Occurs Through Genetic Change Within PopulationsChapter 26.2 - Many Natural Populations Contain High Levels Of Genetic VariationChapter 26.3 - New Species Arise Through The Evolution Of Reproductive IsolationChapter 26.4 - The Evolutionary History Of A Group Of Organisms Can Be Reconstructed By Studying Changes In Homologus CharacteristicsChapter 26.5 - Patterns Of Evolution Are Revealed By Molecular Changes
Book Details
With Genetics: A Conceptual Approach, Ben Pierce brings a master teacher's experiences to the introductory genetics textbook, clarifying this complex subject by focusing on the big picture of genetics concepts and how those concepts connect to one another. The new edition continues the Pierce tradition of pedagogical excellence and scientific currency. In addition, it features a new digital component, SaplingPlus, combining Sapling's acclaimed online homework with an extensive suite of interactive learning resources and course management features.
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Justify reason for the correct statement: All living organisms acquire similar genetic systems, and...In Hopis, the type of albinism is oculocutaneous albinism which affects skin and eyes only. This...Actively dividing eukaryote cells pass through a series of stages collectively called as the cell...Sister chromatid is also known as one half of the chromosome which is duplicated. Dyad is a term...(a) Prophase of mitosis. Mitosis represent a type of cell division in which two daughter cells are...In meiosis I, anaphase I stage includes two homologous chromosomes having centromere which is the...Pictorial representation: Fig.1: Anaphase I Anaphase I comes after metaphase I in meiosis. In...In the given case, let P and Q be alleles of a single gene. Now,PfPf will denote the genotype of...A pair of two socks is compared to the two chromatids of the chromosomes. The replicated chromosomes...
The number 2 is written only once on the die and can be expressed once. The number of chances that...The number 2 is written only once on the die and can be expressed once. The number of chances that...There are total seven children in the family. The probability of obtaining all boys can be...Tabular representation: Table.1: The proportion of possible genotypes formed in offsprings obtained...Geneticists did not agree with the belief that European explorers were the reason for blonde hair....Non-disjunction occurs during cell division when chromosomes do not divide properly, it can occur in...When homozygous flies singed and purple and homozygous flies for normal bristle and eye color are...Female have two X chromosome and male has one. So the genotype of female is Aa Bb Cc X+Xr and the...The sex in bearded lizards is dependent on both the environment and genetics. Sex in the newborn...A cross between the black (BLBL) × bronze (BRBR) plumages: BRBRBL BLBR(Black) BLBR(Black)BL...To investigate the relation between kitey, black and red feather color, crosses were made which are...A cross between RRPP (walnut) × rrpp (single) Parents→ RRPP × rrpp (walnut) (single) ↓ ↓Gametes → RP...Genotypes responsible for beard and beardless phenotype in goats are given in the following table:...B+BbWw male × B+BbWw female ↓...Penetrance can be defined as the ability of the gene to express itself in an individual. The...Pictorial representation: The following figure represents the cross between (D Opd op×d opd op)....Pictorial representation: The cross between (e+ ro+e ro) (f+f) is represented as below: Fig.1: The...The following table represents the resulted progeny of cross: GenotypeNumberRecombinant or non...If pattern of baldness is considered as sex-influenced trait, then the genes responsible for...Duplication is a type of mutation, which results in the duplication or doubling of some part of the...Tabular representation: GametesXWYXRXRXW(Red-eyed female)XRY(Red-eyed male)XW−XW−XW(White-eyed Notch...In the given case, it is nowhere mentioned that Bill is suffering from Down syndrome. 47 chromosomes...In case, if the segregation of translocated chromosome takes place from chromosome 13and 22 then...Allotriploidy arises when a diploid gamete fuses with haploid gamete. There are two possibilities...The two water samples of polluted and unpolluted areas are analyzed and compared to determine the...The two points cross between the genotypes is as follow: RecipientDonorCrossGenotypesThe percent of...Pictorial representation: Figure 1(a) Figure 1(b) Figure 1(c) In figure no 1(a), the F1 generation...Organism and tissueA+GT+CA+TC+GSheep...The DNA is a biomolecule and the reasons of its long term stability are: 1. The structural and...The total cell division in a cell is directly proportional to the lengthof telomeres before the cell...Pictorial representation: fig 1: Pair of homologous chromosomes in a mouse cell. Fig 1: Pair of...α-amanitin is toxic in nature and has adverse effects on humans. It is used as the tool in research...Pictorial representation: Fig.1: 5′ untranslated region RNA containsan 5′ untranslated region at...By referring to figure 15.10 in the textbook, amino acids can be determined for the given mRNA...The codon table represents the codons and coded amino acids: The codon table shows that the amino...(a) Initiation factor-3 The process of translation begins with the initiation stage, which requires...Tabular representation: Table 1: Transcription of a gene in the present or absent of lactose....Tabular representation: Table 1: Transcription of a gene in the present or absent of lactose....The advantage of using mathematical models to study biological processes such as the function of...The fossil studies give evidence that the genetic divergence of chimpanzee and humans occurred...Transition mutation is a type of base-substitution mutation in which either a purine base is...Pictorial representation: The following gel shows that DNA fragments are present after the EcoRI has...The thrifty phenotype hypothesis suggests that if there is a decrease in the fetal development then...In reference to Figure 23.1, Pancreatic cancer is inherited as an autosomal dominant trait in a...The cross between AABB and aabb is as follows: Parents ♂ ♀ AABB × aabb ↓ ↓ Gamates AB ab ↘ ↙ ↓ F1...In the given scenario, the height of various mothers (xi) and daughters (yi) are given. Mean is...Regression coefficient (b) can be calculated as follows: b = covxysx2 Here, covxy is the covariance...To determine the characteristic that would respond best to selection, narrow-sense heritabilities of...Table 1 Represents the frequency for M locus encodes for enzyme malate dehydrogenase are given:...The allele frequency for sickle cell hemoglobin for current generation f(s) is q. q=0.028 The allele...The alcohol presence increases the rate of mutation from AdhS to AdhF allele. The frequency of AdhF...
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