Anatomy & Physiology: The Unity of Form and Function
8th Edition
ISBN: 9781259277726
Author: Kenneth S. Saladin Dr.
Publisher: McGraw-Hill Education
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Chapter 4.2, Problem 8BYGO
Summarize the processing of a protein from the time a ribosome finishes its work to the time a protein is secreted from the cell. What roles do the endoplasmic reticulum and Golgi complex play in this?
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Students have asked these similar questions
Trace the path of a protein synthesized on a ribosome attached to the
rough endoplasmic reticulum (rough ER) as the protein travels to the
exterior of the cell. Name all the subcellular structures that the protein
passes through. In answering this question, assume that the protein is
already produced/synthesized (i.e. don't describe translation).
Using the the enzyme acid hydrolase in the lysosome:
What is the final destination in which the protein will function?
Which features will the protein receive during its manufacture?
What is the primary structure (general)?
Where is the primary structure made?
Where are the secondary and tertiary structures made?
Will the protein travel through any organelles during its manufacture? Which ones?
What would be the overall result if some part of the manufacture process went wrong, such that the protein ended up as nonfunctional?
Describe the mRNA journey through the cell after the nucleus has given the instructions.
Describe how each organelle affects the mRNA journey as it travel through the cell and, ultimately, through the cell membrane.
Organelles you should mention include the nucleus, nuclear membrane, nucleolus, ribosomes, endoplasmic reticulum, cytoplasm, Golgi body, and plasma/cell membrane.
Chapter 4 Solutions
Anatomy & Physiology: The Unity of Form and Function
Ch. 4.1 - What are the three components of a nucleotide?...Ch. 4.1 - What governs the pattern of base paring in DNA?Ch. 4.1 - what is the difference between DNA and chromatin?Ch. 4.1 - Summarize the structural and functional...Ch. 4.1 - The general name of the monomers that compose DNA...Ch. 4.1 - Prob. 2AYLOCh. 4.1 - Prob. 3AYLOCh. 4.1 - How DNA and protein are combined to form...Ch. 4.1 - Prob. 5AYLOCh. 4.1 - HOW RNA differs from DNA in structure and...
Ch. 4.2 - Prob. 5BYGOCh. 4.2 - Describe the roles of RNA polymerase ribosomes,...Ch. 4.2 - What is the difference between genetic...Ch. 4.2 - Summarize the processing of a protein from the...Ch. 4.2 - Prob. 9BYGOCh. 4.2 - Prob. 10BYGOCh. 4.2 - Prob. 1AYLOCh. 4.2 - Prob. 2AYLOCh. 4.2 - The organization of nucleotides into DNA triplets;...Ch. 4.2 - How the genetic code relates mRNA codons to...Ch. 4.2 - The process and outcome of genetic transcription,...Ch. 4.2 - Prob. 6AYLOCh. 4.2 - Prob. 7AYLOCh. 4.2 - Prob. 8AYLOCh. 4.2 - Prob. 9AYLOCh. 4.2 - Prob. 10AYLOCh. 4.3 - Describe the genetic roles of DNA helicase and DNA...Ch. 4.3 - Explain why DNA replication is called...Ch. 4.3 - Define mutation. Explain why some mutations are...Ch. 4.3 - Prob. 14BYGOCh. 4.3 - Prob. 15BYGOCh. 4.3 - Prob. 16BYGOCh. 4.3 - Prob. 1AYLOCh. 4.3 - Semiconservative replication, the enzymes that...Ch. 4.3 - What a mutation is and how a cell detects and...Ch. 4.3 - The four stages of the cell cycle, what occurs in...Ch. 4.3 - Prob. 5AYLOCh. 4.3 - Cytokinesis and how it overlaps but differs from...Ch. 4.3 - Prob. 7AYLOCh. 4.3 - Prob. 8AYLOCh. 4.4 - Why must the carrier of a genetic disease be...Ch. 4.4 - Prob. 18BYGOCh. 4.4 - Prob. 19BYGOCh. 4.4 - Prob. 1AYLOCh. 4.4 - Organization of the karyotype; the number of...Ch. 4.4 - Prob. 3AYLOCh. 4.4 - Prob. 4AYLOCh. 4.4 - Prob. 5AYLOCh. 4.4 - Why a recessive trait can skip a generation, with...Ch. 4.4 - The differences between the genotype, genome, and...Ch. 4.4 - Prob. 8AYLOCh. 4.4 - Prob. 9AYLOCh. 4.4 - Prob. 10AYLOCh. 4.4 - Prob. 11AYLOCh. 4.4 - Prob. 12AYLOCh. 4.4 - Why it cannot be said that dominant alleles are...Ch. 4.4 - Prob. 14AYLOCh. 4 - Production of more than one phenotypic trait by a...Ch. 4 - When a ribosome reads a codon on mRNA, it must...Ch. 4 - Prob. 3TYRCh. 4 - Two genetically identical strands of a metaphase...Ch. 4 - Prob. 5TYRCh. 4 - Genetic transcription is performed by a....Ch. 4 - Prob. 7TYRCh. 4 - Prob. 8TYRCh. 4 - Semiconservative replication occurs during a....Ch. 4 - Mutagens sometimes cause no harm to cells for all...Ch. 4 - The cytoplasmic division at the end of mitosis is...Ch. 4 - Prob. 12TYRCh. 4 - Prob. 13TYRCh. 4 - Prob. 14TYRCh. 4 - Prob. 15TYRCh. 4 - Prob. 16TYRCh. 4 - Prob. 17TYRCh. 4 - The cytoplasmic granule of RNA and protein that...Ch. 4 - Prob. 19TYRCh. 4 - Prob. 20TYRCh. 4 - Prob. 1BYMVCh. 4 - Prob. 2BYMVCh. 4 - Prob. 3BYMVCh. 4 - Prob. 4BYMVCh. 4 - Prob. 5BYMVCh. 4 - Prob. 6BYMVCh. 4 - Prob. 7BYMVCh. 4 - Prob. 8BYMVCh. 4 - Prob. 9BYMVCh. 4 - Prob. 10BYMVCh. 4 - Prob. 1WWTSCh. 4 - Steroids, carbohydrates, and phospholipids are...Ch. 4 - Prob. 3WWTSCh. 4 - Prob. 4WWTSCh. 4 - Prob. 5WWTSCh. 4 - The law of complementary base pairing describes...Ch. 4 - Prob. 7WWTSCh. 4 - All mutations result m the production of defective...Ch. 4 - Prob. 9WWTSCh. 4 - Prob. 10WWTSCh. 4 - Why world the supercoiled, condensed form of...Ch. 4 - Prob. 2TYCCh. 4 - Given the information in this chapter, present an...Ch. 4 - Prob. 4TYCCh. 4 - Prob. 5TYC
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The trans-Golgi network is the site of multiple sorting processes as proteins and lipids exit the Golgi complex. Compare and contrast the sorting of proteins to lysosomes with the packaging of proteins into regulated secretory vesicles such as those containing insulin. Compare and contrast the sorting of proteins to the basolateral versus apical cell surfaces in MDCK cells and in hepatocytes.arrow_forwardImagine a protein which functions in ER but requires modification in the Golgi apparatus before it can achieve that function. Describe the protein’s path through the cell starting with protein in ER, with the help of diagram.arrow_forwardDescribe how proteins enter the endomembrane system through the endoplasmic reticulum, are next sorted by the Golgi Apparatus and how they are targeted and delivered to their final destination (lysosomes, plasma membrane, E.R., etc.)arrow_forward
- What is an analogy for a smooth endoplasmic reticulum?arrow_forwardIf the location in which a protein functions is the endomembrane system then the protein is made on a ribosome attached to the outside of the rough endoplasmic reticulum. As the protein is made it is forced through a pore so that it ends up inside the RER. For each enzyme listed or described below state the kind of ribosome on which it's made (cytosolic, RER). If it's made on a RER ribosome, state the final destination of the protein in the endomembrane system. Protein Ribosome type Location in endomembrane system (if applicable) ACE2 receptor (human protein the SARS-CoV-2 spike protein latches on) A histone protein A mature acid hydrolase that will function as an intracellular lipase Cortisol synthesizing enzyme (hint, cortisol is a steroid lipid) Tubulinarrow_forwardTrace the path of proteins synthesized in the rough endoplasmic reticulum as they are processed, modified, and sorted by the Golgi complex and then transported to specific destinations.arrow_forward
- Discuss the structure and function of ribosomes, the endoplasmic reticulum, and the Golgi apparatus, including functional interrelationships among theseorganelles.arrow_forwardThe endoplasmic reticulum and Golgi apparatus are both membrane-bound organelles found in eukaryotic cells. Which statement describes one way in which the endoplasmic reticulum and the Golgi apparatus work together? The Golgi apparatus assembles mRNA, and the endoplasmic reticulum translates them into proteins. The endoplasmic reticulum assembles mRNA molecules, and the Golgi apparatus translates them into proteins. The Golgi apparatus assembles proteins, and the endoplasmic reticulum modifies and packages them. The endoplasmic reticulum assembles proteins and the Golgi apparatus modifies and packages them.arrow_forwardDescribe the process of protein synthesis and trafficking of a protein, a lysosomal hydrolase, destined to be inside the lysosome. You do not need to detail the mechanism of translation but do state the role of the ribosome in getting your hydrolase to the lysosome. In your description please give some detail on the function and purpose of the organelles the protein will pass through and how it gets from organelle to organelle. In other words what happens to the protein along the way?arrow_forward
- Contrast the structure and functions of the rough and smooth endoplasmic reticulum.arrow_forwardDescribe the process of protein synthesis and trafficking of a protein, a lysosomal hydrolase, destined to be inside the lysosome. You do not need to detail the mechanism of translation but do state the role of the ribosome in getting your hydrolase to the lysosome. Include how the pulse-chase experiment could help demonstrate the path taken by the protein on its way to the lysosome. What is function and purpose of the organelles the protein will pass through and how it gets from organelle to organelle. In other words, what happens to the protein along the way?arrow_forwardMAKE A PROTEIN OR A STEROID AND MAKE IT FUNCTION: BEGINNING AT THE LEVEL OF THE GENE IN THE NUCLEUS DEFINE A GENE THE TRANSCRIBE IT, MOVE IT OUT TO THE RIBOCOMES IN THE CYTOPLASM FOR TRANSLATION. THEN GO THROUGH POST TRANSLATIONAL PORCESSING INVOLVING ALL THE ORGANELLES THAT WE HAVE DISCUSSED IN DETAIL. FINALLY AFTER THE PAST TRANSLATIONALLY PROCESSED PROTEIN IS IN IT'S SECRETORY VESICLE TRANSPORT IT TO THE CYTOPLASMIC MEMBRANE AND SECRETE IT VIA EXOCYTOSIS, DO NO DRAW THE STEPS!!! YOU MUST WRITE THE STEOS OUT IN DETAIL. UPLOAD YOU WORK IN THE PORTAL PLEASE!arrow_forward
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