Chapter 4.3, Problem 8AYLO

Summary Introduction

To discuss:

The regulation of cell cycle by cyclins and cyclin-dependent kinases (Cdks).

Introduction:

Cell cycle is an essential process by which cells increase in number while maintaining its genetic stability. In an organism, it is vital for growth and regeneration. However, it has to be tightly regulated to avoid dire consequences. Unregulated repetitive cell division may lead to cancers that may prove detrimental to the organism. On the other hand, infrequent divisions may end in inadequate growth and regeneration. So the regulation of cell cycle is paramount for the organism’s survival. Cyclins, Cdks, and cell cycle checkpoints are responsible for the regulation of cell cycle.