Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 3, Problem 9QP

Crossing Pea Plants: Mendel’s Study of Single Traits

Sickle cell anemia (SCA) is a human genetic disorder caused by a recessive allele. A couple plan to marry and want to know the probability that they will have an affected child. With your knowledge of Mendelian inheritance, what can you tell them if (1) each has one affected parent and a parent with no family history of SCA or (2) the man is affected by the disorder but the woman has no family history of SCA?

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Mendelian Genetics and Non-Mendelian Genetics: Huntington’s disease, a neurodegenerative genetic disorder that typically becomes noticeable in middle age, is due to an autosomal dominant allele. Sickle cell anemia, on the other hand, is a genetic blood disorder due to a recessive allele. Jillian is a carrier of the allele for sickle cell anemia but has no sign of any neurodegenerative disorder in her family. She married  Jacobwhose father died of Huntington’s disease. His mother, however, is not inflicted with that condition. Neither of his parents exhibit sickle cell anemia. 1. Give the genotypes of Jillian and Jacob.       Assuming that they will have 4 children, what is the probability that: 2. all their children will be normal? 3. they will have a son with Huntington’s disease?  4. they will have a daughter inflicted with both conditions
Considering a common autosomal recessive trait: (Read each statement carefully. Select all of the statements below that are true (that you agree with). Leave any statements that are false (that you do not agree with) un- selected.) the unaffected biological siblings of an affected person should be heterozygotes. an unaffected woman and an affected man have at most a 100% probability of having a affected child. an affected person should have an affected parent. The unaffected offspring of an affected parent must be carriers.
YOUR SISTER DIED FROM TAY-SACHS DISEASE, INHERITED AS A RECESSIVE ALLELE (t). you're married and planning to start your family. you're worried about the disease and decide to have genetic testing to see if you or your spouse is a carrier of the tay-sachs allele. the test results show that you're a carrier of the allele, but your spouse isn't. what is the probability that you and your spouse will have a child with tay-sachs disease? show your work.

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Human Heredity: Principles and Issues (MindTap Course List)

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