Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 27, Problem 7P
Interpretation Introduction
Interpretation:
The effects of Leptin on fat
Concept introduction:
Leptin plays a crucial role in regulating the intake of food, operating system and expenditure of energy. It is evident that leptin involves in the regulation of glucose and metabolism of lipid independent of the anorexic effect in the humans.
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Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of different methods. Make a list of everything that comes to mind.
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- For beta-oxidation of an 18:1 oleate mono-unsaturated fatty acid: - How many Acetyl CoA produced? - How many NADH produced? - How many FADH2 produced? And explain why FADH2 and NADH are different; when they would be the same number in the beta-oxidation for saturated fatty acids.arrow_forward. Glucagon secretion causes inhibition of intracellular acetyl-CoA car- boxylase activity by several mechanisms. Name all you can think of.arrow_forwardDiscuss how the isozymic forms of acetyl CoA carboxylase regulate fatty acid metabolism. Explain the reciprocal regulation of fatty acid production and breakdown, as well as the numerous mechanisms that are used to accomplish this control.arrow_forward
- Role of Carnitine in fatty acid β-oxidationarrow_forwardThe body uses ketone bodies as fuel “during times of extreme starvation” and that ketosis “is an important survival mechanism that maintains high rates of fatty acid oxidation when carbohydrate stores are depleted” but that “it can lead to pathologic conditions.” Summarize what ketosis is metabolically, including figure 16.15 from the text in your summary.arrow_forwardOne metabolic scenario that leads to insulin resistance is the elevation of the conccentration of free fatty acids in skeletal muscle cells. Would you expect increased activity of diacylglycerol acyltransferas (DGAT) to reduce or exacerbate the resistance? Explain.arrow_forward
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