Concept explainers
(a)
Interpretation: To identify whether citrulline or arginine enters the urea cycle first.
Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine. The urea cycle is as follows:
(b)
Interpretation: To identify whether ornithine or aspartate enters the urea cycle first.
Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine. The urea cycle is as follows:
(c)
Interpretation: To identify whether argininosuccinate or fumarate enters the urea cycle first.
Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine. The urea cycle is as follows:
(d)
Interpretation: To identify whether carbamoyl phosphate or citrulline enters the urea cycle first.
Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine. The urea cycle is as follows:

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Chapter 26 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
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