Concept explainers
(a)
Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the skeletal muscle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(b)
Interpretation: To indicate whether the statement “glucose from the liver travels to skeletal muscle as part of the cycle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(c)
Interpretation: To indicate whether the statement “pyruvate is converted to lactate in the liver” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
(d)
Interpretation: To indicate whether the statement “both lactate and pyruvate are present in skeletal muscle” relating to the Cori cycle is true or false.
Concept introduction: Glucose is converted to pyruvate by glycolysis metabolic pathway, pyruvate is further converted to lactate in the skeletal muscle cells by anaerobic reactions. The lactate is diffused into the bloodstream, by which it is transported to the liver. Lactate is reconverted to pyruvate. Gluconeogenesis metabolic pathway uses this pyruvate to synthesize glucose in the liver cells. Glucose is diffused into the bloodstream and is transported back to the active skeletal muscle cells. This cycle is known as the Cori cycle.
The Cori cycle is named after its discoverers, Gerty Radnitz Cori, and Carl Cori.
Want to see the full answer?
Check out a sample textbook solutionChapter 24 Solutions
Bundle: General, Organic, and Biological Chemistry, 7th + OWLv2 Quick Prep for General Chemistry, 4 terms (24 months) Printed Access Card
- Which nutrient provides energy in its most concentrated form?arrow_forwardFor every one glucose molecules, how many high energy molecules are formed in citric acid cycle? A. 2 NADH, 0.5 FADH2, and 0.5 GTP B. 3 NADH, 1 FADH2, and 1 GTP C. 6 NADH, 2 FADH2, and 2 GTP D. 9 NADH, 3 FADH2, and 3 GTP E. None of the abovearrow_forwardGlycolysis, A. is the breakdown of glucose to two pyruvic acid molecules. B. requires the input of two ATP molecules. C. produces two NADH molecules. D. does not require oxygen. E. all of the above.arrow_forward
- . In the electron transport chain, the hydrogen ions enter the inner compartment of mitochondria through special channels formed by: 1. acetyl CoA 2.ATP synthase 3.chromophores 4.coenzyme A 5.oxygenarrow_forwardMuscle does not provide glucose for the brain during times of starvation. Why? You may choose more than one answer. Muscle lacks sufficient glucose stores. Muscle uses the glucose for movement to go find food. Liver provides glucose for brain Glucagon prevents the secretion of glucose Muscle lacks the enzymes necessary to produce free glucosearrow_forwardGlucose is the preferred energy source of the brain, Why?arrow_forward
- 17. In the urea cycle, ions are converted to urea. a. рpyruvate b. sodium C. ammonium O d. glutamatearrow_forwardThe role of oxygen in aerobic respiration is to A. form water that is the medium of all chemical reactions B. combine with free electrons and hydrogen ions from the electron transport chain C. provide transport of electrons from the cystol across the inner membrane of mitochondria D. combine with carbon to form carbon dioxidearrow_forwardThe metabolic pathway of the citric acid cycle is involved in: a. Catabolism of sugars b. Catabolism of fatty acids c. Catabolism of amino acids d. Anabolism of amino acids, fatty acids and glucose O e. All of the abovearrow_forward
- How many electron carrier molecules (both NADH and FADH₂) are made per glucose put in to glycolysis? How many electron carrier molecules (both NADH and FADH₂) are made per pyruvate put in to the Krebs Cycle? How many electron carrier molecules (both NADH and FADH₂) are made by the Krebs Cycle per glucose consumed by the organism? How many electron carrier molecules in total (both NADH and FADH₂) have been made from a single glucose after both glycolysis and the Krebs Cycle? How many electrons are being carried from glucose at this point (Hint: 2 per molecule)?arrow_forwardWhich statements describe electron transport chain events? Two electrons pass between cytochromes through a series of redox reactions. Citrate metabolism results in the formation of one FADH2 and three NADH. NADH releases two hydrogen ions and donates two electrons to coenzyme Q. ATP synthase uses the energy from the redox reactions to generate ATP.arrow_forwardCHOOSE THE CORRECT LETTER. 1.Glycolysis is favored when there is high sugar in the blood. Glycolysis is a catabolic pathway. A. Neither statements are correctB. Only the second statement is correctC. Only the first statement is correctD. Both statements are correctarrow_forward
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage LearningChemistry In FocusChemistryISBN:9781305084476Author:Tro, Nivaldo J., Neu, Don.Publisher:Cengage LearningGeneral, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning
- Organic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningChemistry: Matter and ChangeChemistryISBN:9780078746376Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl WistromPublisher:Glencoe/McGraw-Hill School Pub Co