a) Interpretation: How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown. Concept introduction: The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO 2 followed by hydrolysis. To show: How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

protons. Calculate the mass (in grams) of H3AsO4 (MW=141.9416) needed to produce 3.125 x 1026

Please provide with answer, steps and explanation of ideas to solve.

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 6

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Answer 7

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Answer 8

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 9

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 13

Ch. 20.1 - Give IUPAC names for the following compounds:Ch. 20.1 - Draw structures corresponding to the following...Ch. 20.2 - Prob. 3P Ch. 20.2 - The Ka for dichloroacetic acid is 3.32 Ă— 10-2....Ch. 20.3 - Calculate the percentages of dissociated and...Ch. 20.4 - Which would you expect to be a stronger acid, the...Ch. 20.4 - Dicarboxylic acids have two dissociation...Ch. 20.4 - The pKa of p-cyclopropylbenzoic acid is 4.45. Is...Ch. 20.4 - Prob. 9P Ch. 20.5 - Prob. 10P

Solution Summary: The author explains how benzene can be converted to 2-methyl-2-phenylpropanoicacid through the following steps.

Concept explainers

Want to see the full answer?

Chapter 20 Solutions