a) Interpretation: How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown. Concept introduction: The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO 2 followed by hydrolysis. To show: How to transform benzene to 2-methyl-2-phenylpropanoic acid.

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Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

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Hi!! Please provide a solution that is handwritten. Ensure all figures, reaction mechanisms (with arrows and lone pairs please!!), and structures are clearly drawn to illustrate the synthesis of the product as per the standards of a third year organic chemistry course. ****the solution must include all steps, mechanisms, and intermediate structures as required. Please hand-draw the mechanisms and structures to support your explanation. Don’t give me AI-generated diagrams or text-based explanations, no wordy explanations on how to draw the structures I need help with the exact mechanism hand drawn by you!!! I am reposting this—ensure all parts of the question are straightforward and clear or please let another expert handle it thanks!!

. (11pts total) Consider the arrows pointing at three different carbon-carbon bonds in the molecule depicted below. Bond B 2°C. +2°C. < cleavage Bond A • CH3 + 26. t cleavage 2°C• +3°C• Bond C Cleavage CH3 ZC '2°C. 26. E Strongest 3°C. 2C. Gund Largest BDE weakest bond In that molecule a. (2pts) Which bond between A-C is weakest? Which is strongest? Place answers in appropriate boxes. Weakest C bond Produces A Weakest Bond Most Strongest Bond Stable radical Strongest Gund produces least stable radicals b. (4pts) Consider the relative stability of all cleavage products that form when bonds A, B, AND C are homolytically cleaved/broken. Hint: cleavage products of bonds A, B, and C are all carbon radicals. i. Which ONE cleavage product is the most stable? A condensed or bond line representation is fine. 人 8°C. formed in bound C cleavage ii. Which ONE cleavage product is the least stable? A condensed or bond line representation is fine. methyl radical •CH3 formed in bund A Cleavage

Which carbocation is more stable?

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

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Answer 5

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 6

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Answer 7

Chapter 20.SE, Problem 63AP

Interpretation Introduction

a)

Interpretation:

How to carry out the transformation given, benzene to 2-methyl-2-phenylpropanoic acid, is to be shown.

Concept introduction:

The conversion of benzene to 2-methyl-2-phenylpropanoicacid involves the following steps. i) Conversion of benzene to isopropylbenzene by Friedal-Crafts alkylation. ii) Introduction of bromine in the benzyl carbon using NBS. iii) Conversion to a Grignard reagent iv) Treatment with CO₂ followed by hydrolysis.

To show:

How to transform benzene to 2-methyl-2-phenylpropanoic acid.

Answer 8

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 9

Interpretation Introduction

b)

Interpretation:

How to carry out the transformation given, conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid, is to be shown.

Concept introduction:

The steps involved in the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid are i) conversion of the ketone to a tertiary alcohol using a Grignard reagent ii) conversion of the alcohol to a bromide iii) conversion of the bromide to a Grignard reagent iv) treatment of the Grignard reagent with CO₂ and hydrolysis to get the carboxylic acid.

To show:

How to carry out the conversion of cyclohexanone to 1-phenylcyclohexanecarboxylic acid.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 20.1 - Give IUPAC names for the following compounds:Ch. 20.1 - Draw structures corresponding to the following...Ch. 20.2 - Prob. 3P Ch. 20.2 - The Ka for dichloroacetic acid is 3.32 Ă— 10-2....Ch. 20.3 - Calculate the percentages of dissociated and...Ch. 20.4 - Which would you expect to be a stronger acid, the...Ch. 20.4 - Dicarboxylic acids have two dissociation...Ch. 20.4 - The pKa of p-cyclopropylbenzoic acid is 4.45. Is...Ch. 20.4 - Prob. 9P Ch. 20.5 - Prob. 10P

Solution Summary: The author explains how benzene can be converted to 2-methyl-2-phenylpropanoicacid through the following steps.

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