The given transformation in the presence of sodium ethoxide is to be explained. Concept introduction: Electrophiles are electron deficient species that have positive or partially positive charge. Lewis acids are electrophiles that accept electron pair. Nucleophiles are electron rich species that has negative or partially negative charge. Lewis bases are nucleophiles that donate electron pair. Free radical is an atom, molecule, or ion that has an unpaired electron, which makes it highly chemically reactive. Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction. Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction. Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules. The carbon-carbon bond forming reaction, useful for the synthesizing of beta keto ester, is known as Claisen condensation reaction. In Claisen condensation, reaction occur between two esters, a carbon-carbon bond formation takes place which leads to the formation of β − keto ester. Esters containing only one alpha hydrogen do not undergo Claisen condensation reaction. A Dieckmann condensation is also known as intramolecular Claisen condensation. Five and six membered rings are easily prepared by Dieckmann condensation. The rings with members less than five are disfavored due to strain.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 31P

Interpretation Introduction

Interpretation:

The given transformation in the presence of sodium ethoxide is to be explained.

Concept introduction:

Electrophiles are electron deficient species that have positive or partially positive charge. Lewis acids are electrophiles that accept electron pair.

Nucleophiles are electron rich species that has negative or partially negative charge. Lewis bases are nucleophiles that donate electron pair.

Free radical is an atom, molecule, or ion that has an unpaired electron, which makes it highly chemically reactive.

Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction.

Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction.

Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules.

The carbon-carbon bond forming reaction, useful for the synthesizing of beta keto ester, is known as Claisen condensation reaction.

In Claisen condensation, reaction occur between two esters, a carbon-carbon bond formation takes place which leads to the formation of β− keto ester.

Esters containing only one alpha hydrogen do not undergo Claisen condensation reaction.

A Dieckmann condensation is also known as intramolecular Claisen condensation.

Five and six membered rings are easily prepared by Dieckmann condensation.

The rings with members less than five are disfavored due to strain.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Which of the reaction conditions could afford the following transformation?

For each reaction, give the expected substitution product, and predict whether the mechanism will be predominantly first order (SN1) or second-order (SN2). (a) isobutyl bromide + sodium methoxide

Enamines can serve as enolate surrogates in reactions at the a-carbon. In the reaction sequence, the structures of the enamine addition product – the initial iminium and its neutral tautomer – are shown. Draw the structures of the enamine and alkyl bromide reactants that would combine to form these intermediates, and draw the structure of the final product, obtained via hydrolysis of the neutral intermediate. iminium intermediate neutral intermediate tautomerization N. Reactants H20 hydrolysis product Draw the enamine and alkyl bromide reactants. Draw the hydrolysis product. ZI