Chapter 19, Problem 45P

Interpretation Introduction

Interpretation:

Using any other necessary reagents, the compounds (a) and (b) from cyclopentanone and the compound (c) from diethyl malonate are to be synthesized.

Concept introduction:

The synthesis of mono di-substituted acetic acid that is a useful counterpart of acetoacetic ester synthesis is called malonic ester synthesis.

In malonic ester synthesis, the starting material is malonic ester and the most commonly used malonic ester is diethyl malonate.

An aldol reaction occurs in protic solvent with a base such as hydroxide or alkoxide.