The type of lead poisoning by which its poisonous effect on enzymes can be stopped by chelation therapy with EDTA and its reason should be determined. Concept Introduction: Enzyme: It is a protein or a molecule which can act as a catalyst for a biological reaction. Does not affect the equilibrium point of the reaction. Active site of the enzyme is the region where the reaction takes place. Enzyme’s activity can be specific which means the activity is limited to a certain substrate and a certain type of reaction and it is referred to as specificity of the enzyme. Enzyme inhibitors: The substance which slows or stops the action of an enzyme is called enzyme inhibitors. It can be used as drugs and an example is AZT which is used to treat HIV. The competition of an enzyme can be reversible or irreversible and in reversible inhibition, the inhibitor can leave and in irreversible inhibition, the inhibitor remains permanently bound. Reversible Competitive inhibition: It is a type of inhibition occurs when the inhibitor resembles very much to the substrate and thus prevents the substrate binding. Irreversible competitive inhibition: It is a type of inhibition in which an inhibitor forms covalent bonds to the active site and thereby permanently blocking it.

Question

Want to see the full answer?

Answer 1

Question

Chapter 19, Problem 19.63AP

Interpretation Introduction

Interpretation:

The type of lead poisoning by which its poisonous effect on enzymes can be stopped by chelation therapy with EDTA and its reason should be determined.

Concept Introduction:

Enzyme:

It is a protein or a molecule which can act as a catalyst for a biological reaction.

Does not affect the equilibrium point of the reaction.

Active site of the enzyme is the region where the reaction takes place.

Enzyme’s activity can be specific which means the activity is limited to a certain substrate and a certain type of reaction and it is referred to as specificity of the enzyme.

Enzyme inhibitors: The substance which slows or stops the action of an enzyme is called enzyme inhibitors.

It can be used as drugs and an example is AZT which is used to treat HIV.

The competition of an enzyme can be reversible or irreversible and in reversible inhibition, the inhibitor can leave and in irreversible inhibition, the inhibitor remains permanently bound.

Reversible Competitive inhibition: It is a type of inhibition occurs when the inhibitor resembles very much to the substrate and thus prevents the substrate binding.

Irreversible competitive inhibition: It is a type of inhibition in which an inhibitor forms covalent bonds to the active site and thereby permanently blocking it.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

9) Below, there is a representation of an SDS-PAGE gel. Assuming the samples in the MW standard have masses of: 66 kDa, 45 kDa, 36 kDa, 29 kDa, 24 kDa, 20.1 kDa, and 14.2 kDa, a) Figure 4: indicate where each of the measurements were taken and label as in II.6. figure 2 above. b) As in II.7. Table 1 above create Table 2 using the data below. Determine the r.f. values for the MW standards, plot the relative mobility versus the log of the mass for the standards, and use the best fit straight line to determine the molecular weights of the proteins in the whey, peak 1, and peak 2 lanes. (5 pts—this will be scaled up appropriately if your gel did not develop properly) dye MW Whey Peak 1 Peak 2

what are the different classes and some examples of neuroprotectants that can be used to treat, prevent, or combat neurotoxicity/a neurotoxicant...for example, antioxidants, nutraceuticals, etc.,..?

Imagine that aldolase can react with the seven carbon molecule Sedoheptulose-1,7-bisphosphate (below). Use the mechanism to predict the two products generated. Please draw out the stereochemistry in a fischer projection.