Chapter 19, Problem 19.31AP

Interpretation Introduction

Interpretation:

The acidic and basic amino acid in the active site in the given diagram has to be determined.

Concept Introduction:

The enzyme can acts as a catalyst due to following capabilities given below:

• It can bring substrates and catalytic sites together.
• It gives acidic, basic or other groups required for catalysis.
• For the reaction to occur, enzyme holds substrate at exact distance and in exact orientation.
• It lowers the energy barrier.

Acidic amino acids: The amino acids which can donate ${\text{H}}^{\text{+}}$ and examples include aspartic acid, glutamic acid.

Basic amino acids: The amino acids which can accept ${\text{H}}^{\text{+}}$ and examples include histidine and lysine.