Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 18, Problem 5TYK
A cDNA and a cloned fragment of genomic DNA share sequences from a mouse gene. What differences do you expect to see between the cDNA and genomic DNA sequences?
a. None; they should be identical.
b. The genomic DNA might have an intron or introns.
c. The genomic DNA might have promoter sequences.
d. The genomic DNA might have a poly(A) tail.
e. Both b and c are correct.
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Could a frameshift mutation result in the production of a larger than wild type protein?
A.Yes, but it’s likely only if the frameshift occurs early in the coding sequence.
B.Yes, but it’s likely only if the frameshift occurs late in the coding sequence.
C.Yes, by producing a longer than normal transcript
D.Yes, by producing larger than normal Okazaki fragments.
E.No, frameshift always results in the occurrence of STOP codons and premature termination of translation
a. The reading frame DNA sequence is:
b. The mRNA sequence is:
c. The polypeptide sequence is:
A disease in frogs which causes their tongue to fall out of their mouths is killing the frog population in LA County. You obtain a dead frog and isolate its gene Xf. When you sequence this mutated gene, you find that the last ‘G’ at the end of the first line of this sequence has been deleted (i.e. the G at position 86). In order to determine how this mutation changes the resulting polypeptide, write the mutated polypeptide sequence in the space below. What kind of mutation was produced?
The mutated polypeptide sequence is
What kind of mutation was produced?
central dogma of molecular biology describe the flow of information in the cell.There are also exceptions to the central dogma. Which of the following examples is inconsistent with the flow of genetic information in the cell?
a. from DNA to mRNA
b.from mRNA to protien
c.from protien to DNA
d.from DNA to rRNA
e. from DNA to tRNA
Chapter 18 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 18.1 - What features do restriction enzymes have in...Ch. 18.1 - Prob. 2SBCh. 18.1 - What information and materials are needed to...Ch. 18.2 - What is a transgenic organism?Ch. 18.2 - Prob. 2SBCh. 18.3 - What is a restriction fragment length polymorphism...Ch. 18.3 - Prob. 2SBCh. 18.3 - Prob. 3SBCh. 18 - Prob. 1TYKCh. 18 - Prob. 2TYK
Ch. 18 - Why are antibiotic resistance markers such as ampR...Ch. 18 - After a polymerase chain reaction (PCR), agarose...Ch. 18 - A cDNA and a cloned fragment of genomic DNA share...Ch. 18 - Prob. 6TYKCh. 18 - Which of the following is not true of somatic cell...Ch. 18 - Prob. 8TYKCh. 18 - Prob. 9TYKCh. 18 - Prob. 10TYKCh. 18 - Prob. 11TYKCh. 18 - Discuss Concepts A forensic scientist obtained a...Ch. 18 - 13. Suppose a biotechnology company has developed...Ch. 18 - Prob. 14TYKCh. 18 - You learned in the chapter that an STR locus is a...
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- The promoter consensus sequence at the -10 BOX in the bio gene in E. coli was TAGACT; however, a transversion occurred which changed the G nucleotide to T, what outcome(s) are likely? a. transcription levels would decrease because the promoter would be weaker b. nothing would happen because the promoter would not change the mRNA sequence c. the mutation would block RNA polymerase from binding to the DNA d. transcription levels would increase because the promoter would be stronger e. the bio gene does not require a functional promoterarrow_forwardThe original DNA base sequence is 5’-AGCGTTACCGT-3’; a mutation in the DNA strand results in the base sequence 5’-AGGCGTTACCGT-3’. What can you conclude about the mutation? A. It is a frameshift mutation. B. It is a silent mutation. C. It is a deleterious mutation. D. It may result in a single amino acid change in the protein being coded for by this base sequence.arrow_forwardWhat are the most highly-conserved regions of human DNA (when compared to similar DNA sequences in closely-related animals)? A. transposons B. non-transcribed spacers C. introns D. pseudogenes E. exonsarrow_forward
- Would it be possible to start synthesizing the daughter DNA strand without assembling the RNA primer first? Why? Why not?arrow_forwardWhich of the following is true about the enzyme telomerase? A. It is found only in adult cells. B. It is responsible for telomere shortening. C. It can re-establish telomere length. D. It may speed up the aging process. E. It is expressed at low levels in cancer cells.arrow_forwardA genetic researcher notices that individuals with a particular genetic disease have a shortened version of key protein involved in the diseased biochemical pathway. Which of the following mutations is most likely to result in the premature termination of protein synthesis? A. The disease is caused by a silent mutation. B. The disease is caused by a frameshift mutation. C. The disease is caused by a missense mutation. D. The disease is caused by a nonsense mutation.arrow_forward
- Which of the following plays a major part in determining whether or not RNA polymerase will transcribe a parti sequence? Select all that apply. A. A ribosome is already bonded to the gene sequence B. A complete set of transcription factors bind to DNA associated with that gene C. The chromatin structure is loosened in the region of that gene D. RNA polymerase binds to the promoter of that gene ..arrow_forwardShown below is diagram of RNA polymerase undergoing the process of transcription: This transcript: O Select one: a. None of these choices is correct. O b. has a sequence complementary to the top strand of the DNA. c. has a sequence identical to the top strand of the DNA. d. has a sequence complementary to the bottom strand of the DNA. e. has a sequence identical to the bottom strand of the DNA. f. It is not possible to determine, because not enough information has been provided. g. More than one of these choices is correct. MacEarrow_forwardWhy can the transcriptome not be used to predict the proteome with complete accuracy? a. It cannot be sequenced like the genome can be. b. The transcriptome is too dynamic to be used to make predictions. c. Not all genes are transcribed. d. Many transcripts are alternatively spliced to produce different proteins.arrow_forward
- Which of the following statements are correct about DNA Repair in mammals (select all that apply)? A. The Mismatch Repair System is primarily responsible for repairing covalent chemical modification of DNA bases B. Over 150 proteins are involved in DNA Repair C. Without DNA repair systems we would all likely die of cancer at a young age. D. Many DNA Repair enzymes are weakly expressed in tissues of the central nervous system making the CNS more susceptible to some carcinogens. E. Cancer cells possess a mutator phenotypearrow_forwardHDAC's are important enzymes involved in the regulation of Gene expression. This is because a. They create the Z form of DNA by removing acetyl groups from cytosines. b. they create euchromatic structure by adding acetyl groups to cytosine. c. they add methyl groups from histones creating less gene expression. d. they remove acetyl groups from histones creating less gene expression. e. they add methyl groups onto cytosines on DNA and create a heterochromatic structure.arrow_forwarda. Give the sequence of mRNA that would be transcribed off of the bottom strand and label its 5' and 3' ends. b. translate this RNA sequence in 1a into a protein sequence c. Give the sequence of mRNA that would be transcribed off of the top strand and label its 5' and 3' ends. d. Translate this RNA sequence in 1c into a protein sequencearrow_forward
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Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License