(a)
Interpretation: The number of stereogenic centers present in the product is to be determined.
Concept introduction: A carbon atom which is bonded to four different groups is termed as chiral center or stereogenic center. The groups around the stereogenic center are prioritized on the basis of
(b)
Interpretation: The product formed from the given reaction exhibit optical activity or not is to be predicted and explained.
Concept introduction: The replacement or substitution of one
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- Rank the compounds in each group according to their reactivity toward electrophilic substitution. 1 = most reactive; 3 = least reactive. a. toluene methoxybenzene fluorobenzene b. p-bromonitrobenzene ✓nitrobenzene ✓phenolarrow_forwardWhat ketone could be used to prepare 3-methylpentan-3-ol via a Grignard reaction with CH3MgBr? a.) Pentan-2-oneb.) Pentan-3-onec.) Pentan-4-one d.) acetonearrow_forwardWhat stereoisomers are formed in the following reactions? Which stereoisomer is the major product? a. the acid-catalyzed dehydration of 1-pentanol to 2-pentene b. the acid-catalyzed dehydration of 3,4-dimethyl-3-hexanol to 3,4-dimethyl-3-hexenearrow_forward
- 5. Which of these two compounds has a higher boiling point? Cyclopentanol The phenomenon responsible for that compound's higher boiling point is: cyclohexane 6. The electrophile in this reaction is: CH3CI benzene AICI3 a) CI* b) Cr c) CH,E- d) CH3*arrow_forwardConsider the following nucleophilc substitution. LOCH3 Br OCH3 в A a. Identify the reaction conditions A and specify the reaction mechanism for the nucleophilic substitution. Explain your choice. b. Explain why the transformation does not give rise to significant elimination. c. Which product(s) B is formed in the reaction? Please specify the stereochemistry clearly with reference to the reaction mechanism.arrow_forward2. The reaction of 2-bromo-2-methylbutane with sodium ethoxide at 50 °C leads to the formation of 2-methyl-2-butene.arrow_forward
- 1. Draw the structure of sodium (E) 2-bromo-3-iodo-2-octenoate. 2. Give the IUPAC name of this compound, including stereochemistry. 3. Draw the most stable chais CH³arrow_forward1. What product is expected to form in an Sy2reaction of OH¯with (R)-2-bromobutane? Show the stereochemistry of the reactant and the product. 2. What product is expected to form from the SN2reaction of 1-bromopentane with а. КОН? B. Nal? 3. What product would you expect to obtain from a nucleophilic substitution reaction of (S)-2- bromohexane with CH3CO,? Assume that inversion configuration occurs, and show the stereochemistry of both reactant and product? 4. Predict whether each of the following substitution reactions is likely t Sylor SN2. CI OAc CH3CO, Na+ CH3CO2H, H20 а. CH2BR CH2OAC CH3CO2- Na+ DMF b. OH HCI CI CH3OH с. CH3 CH3 Na+ SCH3 H2C=CH2B d. H2C=CCH,SCH3 CH3CN 5. Setting aside the double bond stereochemistry, what products would you expect from elimination reactions of the following alkyl halides? CH3 ÇI CH3 CH3CHCH2-C-CHCH3 ČH3arrow_forwardDraw a structure corresponding to each name. a.p-dichlorobenzene b.p-iodoaniline c. o-bromonitrobenzene d.2,6-dimethoxytoluene e.2-phenylprop-2-en-1-ol f.trans-1-benzyl-3-phenylcyclopentanearrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning