Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 17, Problem 22TYK
Summary Introduction
Introduction: Mutations refer to the alteration in the genome of an organism. Mutation is caused as a result of an error in the replication process of DNA. Mutations can be neutral, beneficial, or harmful for any organism. The alterations caused as a result of mutations is permanent in nature.
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A normal strand of DNA reads: 5'-AGTCAA-3'. If a mutation occurs that alters that DNA sequence to 5'-ACTCAA-3', that mutation could be characterized as a
O a. Base substitution
O b. Frameshift mutation
O c. Point mutation
O d. Both A&B
O e. Both A & C
Consider this sequence below:
GAG TAC ACG AGT GGA
Which of the following options is an example of a non-synonymous point mutation? (remember to translate to mRNA!)
A. GAG TAC AAT CGA GTG GA
B. GAG TAC ACG GGT GGA
C. GAG TAC A–G AGT GGA
D. GAG TAC ACG AGA GGA
-Write down the complementary DNA sequence.
TACCTAGCG CACATGTAGGTGGGCAAAGTT
-Write down the complementary mRNA sequence for each of the following DNA sequence.
A: TACCTAGCGCACATGTAGGTGGGCAAAGTT
B:
TAC ATG GTT ACA GTC TAT TAG ATG CTA TTT ACT TAG
-If the first G changes to A what kind of mutation will happen? Show the change in amino acid sequence.
This is base substitutions involve the replacement of one nucleotide with another. And it changes one amino acid coding, producing a missense mutation
TAC CTA GCA CAC ATGTAGGTGGGCAAAGTT
TAC CTA ACACACATGTAGGTGGGCAAAGTT
Chapter 17 Solutions
Study Guide for Campbell Biology
Ch. 17 - a. In what three ways does RNA differ from DNA? b....Ch. 17 - Prob. 2IQCh. 17 - Prob. 3IQCh. 17 - How does the mRNA that leaves the nucleus differ...Ch. 17 - Prob. 5IQCh. 17 - In the following diagrams of polypeptide...Ch. 17 - What determines if a ribosome becomes bound to the...Ch. 17 - Define the following terms and explain what type...Ch. 17 - You have been introduced to several types of RNA...Ch. 17 - Prob. 2SYK
Ch. 17 - What is the genetic code? Explain redundancy and...Ch. 17 - Prepare a concept map showing the types and...Ch. 17 - Prob. 1TYKCh. 17 - Transcription involves the transfer of information...Ch. 17 - Prob. 3TYKCh. 17 - Prob. 4TYKCh. 17 - Which of the following is a statement of the...Ch. 17 - Prob. 6TYKCh. 17 - Prob. 7TYKCh. 17 - Prob. 8TYKCh. 17 - Which of the following is true of RNA processing?...Ch. 17 - Prob. 10TYKCh. 17 - Prob. 11TYKCh. 17 - Prob. 12TYKCh. 17 - Prob. 13TYKCh. 17 - Prob. 14TYKCh. 17 - What type of bonding is responsible for...Ch. 17 - Prob. 16TYKCh. 17 - Prob. 17TYKCh. 17 - Prob. 18TYKCh. 17 - Prob. 19TYKCh. 17 - Prob. 20TYKCh. 17 - Prob. 21TYKCh. 17 - Prob. 22TYKCh. 17 - Prob. 23TYKCh. 17 - Prob. 24TYKCh. 17 - Prob. 25TYKCh. 17 - Prob. 26TYKCh. 17 - Prob. 27TYKCh. 17 - Prob. 28TYK
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- Which of the following represents the sequence of an RNA transcript for which the template strand of DNA has the sequence: GTACTGGCTAGCTGCTAGAA? Note all sequences are written 5'-3'. DA. GUACUGGCUAGCUGCUAGAA B. UUCUAGCAGCUAGCCAGUAC с. ТТСТАGCAGCTAGCCAGTАС D. GTACTGGCТAGCTGCTAGAАarrow_forward1 An Amino Acid Sequence Leu - Tyr - Gly-Gly - Val Which of the following changes to the mRNA that produces the amino acid sequence shown above would be characterized as a missense mutation? Select one: O A. CUC UAG GGU GGC GUA OB. CUC UAC GGG GGC GUA OC. CUC UAC GGU GGC GCU O D. CUC UAU GGU GGC GUAarrow_forwardNow the gene sequence was changed in a different way, such that instead of producing a mRNA with the codon UCG, it produced an mRNA with UAG. This change (UCG to UAG) is considered a O a. missense mutation O b. frame-shift mutation O c. silent mutation O d. nonsense mutationarrow_forward
- What type of mutation causes the "mutant" variety of the PTC gene? a A point mutation which lead to a nonsense mutation b A addition mutation which lead to a frameshift c A substitution mutation which lead to a missense mutation d A deletion mutation which lead to a SNP mutationarrow_forwardThe sequence of a gene was changed (mutated) such that, instead of producing a mRNA with the codon CUU, it produced an mRNA with CUG. This change (CUU to CUG) is considered a O a. silent mutation O b. missense mutation O c. nonsense mutation O d. frame-shift mutationarrow_forwardwhat is the correct order of the point mutations? a. bafecd b. fcdbea c. dfaebc d. cbadef e. efcadbarrow_forward
- Given is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’ a. What is the complementary strand? b.Deduce the mRNA in this coding region. c.What is the amino acid sequence based on this mRNA? d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?arrow_forwardwhich of these describes the symptoms of the disease(s) caused by mutations in this gene CAGATTGTGAAGAGGTCTCTTGA? Select all that apply a. Thread-like blood vessels in eyes b. Excessive bleeding c. Dwarfism d. UV light sensitivity e. sunburn f. Bruisesarrow_forwardWhich of the following is/are a transition mutation(s)? (select any that apply) A to T A to G C to G A to C C to Aarrow_forward
- E The arrow in the diagram below indicates the direction of transcription. BTTL c. A ATGCCGCA AUGCCCCAAUCUG TACGGCGTTAGAC OA OB с Q Search Which letter indicates the 5' end of the DNA template strand? R F TTCACGCACTCATSTOFACCACGTA T G Direction of synthesis- CG STACATGAGIAC LOC Y H Krit & 7 FO U 99+ * 8 D ATEGTGCAT CVBNM MO DE 79 Alt F:-10 KL E 0 P ^ @ ¹ F12 Ctrl 10:37 AM 4/8/2023 10arrow_forwardA small section of bacterial DNA template (anti-sense) strand has the following nucleotide sequence: AAG TAT TAT GCA A mutation in the above sequence involved the insertion of a single base, leading to a shift in the reading frame of the gene, resulting in altered amino acids downstream from the insertion. Which of the following gene sequences exemplifies the mutation described above? a. AAG CTA TTA TGC A b. AG TAT TAT GCA c. AAG TATU TAT GCA d. AAG TAT TAGT GCAarrow_forwardThe following is the DNA sequence of the entire protein-coding region for some small gene in a eukaryote. Shown is the coding strand. The first row is the original sequence with no mutations. Subsequent rows represent a single mutation. Mutation DNA Sequence ..ATGGGCGAGGTATTATA G.. 3' None 5' A ..A TGGGCGAGATATTATA G.. 3' 5' B ..ATGGG CGAGGT ACTAT A G.. 3 5' 5'..A TGGC C GAGGTATTATAG.. 3' The region without a mutation is transcribed, and then translated. Give the protein that is translated from this section of DNA. Use the single letter abbriviations for amino acids with no spaces. N- -C Determine the molecular basis for each mutation and what effect there would be on the protein. Mutation Molecular Basis Effect on Protein A Transition Transition Transversion Nonsense Synonymous Nonsynonymous Readthrougharrow_forward
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