The pH value required to carry out the imine formation if the pKa value of protonated amine is 9.0 has to be predicted. Concept introduction: Aldehydes and ketones on reaction with amine gives imine, also called as schiff’s base when the nitrogen atom is attached to the alkyl group instead of hydrogen atom. The carbonyl group ( C = O ) of the ketone or aldehyde group is converted into ( C = N ) during imine formation. The general reaction of imine fomrtaion is given as, The imine formation is pH dependent thus the pH of the reaction must be carefully controlled.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 16.8, Problem 29P

Interpretation Introduction

Interpretation:

The pH value required to carry out the imine formation if the pKa value of protonated amine is 9.0 has to be predicted.

Concept introduction:

Aldehydes and ketones on reaction with amine gives imine, also called as schiff’s base when the nitrogen atom is attached to the alkyl group instead of hydrogen atom.

The carbonyl group (C=O) of the ketone or aldehyde group is converted into (C=N) during imine formation.

The general reaction of imine fomrtaion is given as,

The imine formation is pH dependent thus the pH of the reaction must be carefully controlled.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Can any functional groups on Risperidone ionize? If so, which ones? Under what conditions? What are the pKa values of these functional groups? Write the structures in their correct ionization state at physiological pH.

You are planning to carry out a reaction that produces protons. The reaction will be buffered at pH = 10.5. Would it be better to use a protonated methylamine/methylamine buffer or a protonated ethylamine/ethylamine buffer? (pKa of protonated methylamine = 10.7; pKa of protonated ethylamine = 11.0)

Most of the pKa values given in this text were determined in water. How would the pKa values of carboxylic acids, alcohols, ammonium ions (RNH32) , phenol, and an anilinium ion (C6H5NH32) change if they were determined in a solvent less polar than water?

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 16.8, Problem 29P

Interpretation Introduction

Interpretation:

The pH value required to carry out the imine formation if the pKa value of protonated amine is 9.0 has to be predicted.

Concept introduction:

Aldehydes and ketones on reaction with amine gives imine, also called as schiff’s base when the nitrogen atom is attached to the alkyl group instead of hydrogen atom.

The carbonyl group (C=O) of the ketone or aldehyde group is converted into (C=N) during imine formation.

The general reaction of imine fomrtaion is given as,

The imine formation is pH dependent thus the pH of the reaction must be carefully controlled.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 16.8, Problem 29P

Interpretation Introduction

Interpretation:

The pH value required to carry out the imine formation if the pKa value of protonated amine is 9.0 has to be predicted.

Concept introduction:

Aldehydes and ketones on reaction with amine gives imine, also called as schiff’s base when the nitrogen atom is attached to the alkyl group instead of hydrogen atom.

The carbonyl group (C=O) of the ketone or aldehyde group is converted into (C=N) during imine formation.

The general reaction of imine fomrtaion is given as,

The imine formation is pH dependent thus the pH of the reaction must be carefully controlled.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 16.8, Problem 29P

Interpretation Introduction