Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 14, Problem 6TYK
Summary Introduction
Introduction:
Meselson and Stahl experiment explained the replication of DNA (deoxyribonucleic acid) to be semiconservative. The bacteria was grown in a medium containing a heavy isotope of nitrogen and then the bacteria was reproduced in a medium having a light isotope of nitrogen. After each generation, the DNA was centrifuged, in order to separate the DNA molecules on the basis of its density. The result demonstrated a semiconservative replication of the DNA.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 14 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 14.1 - Prob. 1SBCh. 14.2 - Prob. 1SBCh. 14.2 - Prob. 2SBCh. 14.2 - Prob. 3SBCh. 14.2 - Prob. 4SBCh. 14.3 - What is the importance of complementary base...Ch. 14.3 - Why is a primer needed for DNA replication? How is...Ch. 14.3 - DNA polymerase III and DNA polymerase I are used...Ch. 14.3 - Prob. 4SBCh. 14.4 - Why is a proofreading mechanism important for DNA...
Ch. 14 - Working on the Amazon River, a biologist isolated...Ch. 14 - Prob. 2TYKCh. 14 - Pyrimidines built from a single carbon ring are:...Ch. 14 - Which of the following statements about DNA...Ch. 14 - Which of the following statements about DNA is...Ch. 14 - Prob. 6TYKCh. 14 - Prob. 7TYKCh. 14 - Prob. 8TYKCh. 14 - Prob. 9TYKCh. 14 - Prob. 10TYKCh. 14 - Discuss Concepts Eukaryotic chromosomes can be...Ch. 14 - Prob. 12TYKCh. 14 - Prob. 13TYKCh. 14 - Discuss Concepts During replication, an error...Ch. 14 - Design an Experiment Design an experiment using...Ch. 14 - Prob. 16TYKCh. 14 - Prob. 1ITDCh. 14 - Prob. 2ITD
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