Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 14, Problem 13TYK
Summary Introduction
To review:
The reason for the growth of antibiotic resistance in bacteria among similar other bacteria that are killed by the antibiotic.
Introduction:
The chemicals or bioactive molecules that have the potential to kill other bacteria are termed as antibiotics. Furthermore, they are used to treat against bacterial infections. Some bacteria develop resistance genes and become resistant to antibiotics. Thus, such bacteria can survive while sensitive bacteria die in the presence of antibiotics.
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Considering the proclivity of bacteria to share genetic information, discuss the concerns behind phenomena such as antibiotic resistance. In other words, why might it be a bad idea to not finish your antibiotic therapy as prescribed by your physician? Some people think that "saving some for later" is a good idea. Why might that not be the case?
please do (i)
Researchers are designing several experiments to test the ability of Salmonella bacteria to develop antibiotic resistance. A culture of Salmonella bacteria is exposed to the same concentrations (200 mg/L) of an antibiotic for four days. The table shows the number of isolated resistant bacteria over a four-day period. Which of the following statements best explains these results?
A - The bacteria were not affected by the antibiotic.
B - After being exposed to the antibiotic, the bacteria altered their DNA.
C - A new species of bacteria emerged after the antibiotics were introduced.
D - Random mutations led some bacteria to be resistant and, over time, they increased in the population.
Chapter 14 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 14.1 - Prob. 1SBCh. 14.2 - Prob. 1SBCh. 14.2 - Prob. 2SBCh. 14.2 - Prob. 3SBCh. 14.2 - Prob. 4SBCh. 14.3 - What is the importance of complementary base...Ch. 14.3 - Why is a primer needed for DNA replication? How is...Ch. 14.3 - DNA polymerase III and DNA polymerase I are used...Ch. 14.3 - Prob. 4SBCh. 14.4 - Why is a proofreading mechanism important for DNA...
Ch. 14 - Working on the Amazon River, a biologist isolated...Ch. 14 - Prob. 2TYKCh. 14 - Pyrimidines built from a single carbon ring are:...Ch. 14 - Which of the following statements about DNA...Ch. 14 - Which of the following statements about DNA is...Ch. 14 - Prob. 6TYKCh. 14 - Prob. 7TYKCh. 14 - Prob. 8TYKCh. 14 - Prob. 9TYKCh. 14 - Prob. 10TYKCh. 14 - Discuss Concepts Eukaryotic chromosomes can be...Ch. 14 - Prob. 12TYKCh. 14 - Prob. 13TYKCh. 14 - Discuss Concepts During replication, an error...Ch. 14 - Design an Experiment Design an experiment using...Ch. 14 - Prob. 16TYKCh. 14 - Prob. 1ITDCh. 14 - Prob. 2ITD
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- To promote genetic diversity in bacteria, it has been found that some species have a genetic mechanism that allows them to increase their mutation rate during DNA replication. A scientist hypothesizes that the functions of the following two enzymes would be impacted by this mechanism. In each case, state if you agree and provide a reason for your answer. i) DNA primase ii) DNA polymerase IIIarrow_forwardExplain how cells activate nucleic acids for polymerization. Explain why DNA is stable and why its structure dictates its replication mechanism. Explain why many RNA molecules exhibit tertiary structure, while most DNA molecules do not. Explain how DNA replication occurs from structural and enzymatic perspectives. Develop an understanding of nucleic acid biology outside a natural biological context (such as PCR, etc.)arrow_forwardplease do (ii)arrow_forward
- To promote genetic diversity in bacteria, it has been found that some species have a genetic mechanism that allows them to increase their mutation rate during DNA replication. A scientist hypothesizes that the functions of the following two enzymes would be impacted by this mechanism. In each case, state if you agree and provide a reason for your answer. i) DNA primaseii) DNA polymerase IIIarrow_forwardDescribe the structure of a bacterial genome, and explain how it differs from a eukaryotic genome. Explain what a plasmid is, and describe the role of plasmids in the spread of antibiotic resistance genes. Explain how bidirectional semiconservative DNA replication copies the circular chromosome of a bacterium during cell division. Explain the steps of replication by DNA polymerase, including initiation, elongation, and termination. Explain the different kinds of mutations and how they occur.arrow_forwardWhich of the following statements regarding Nucleotide Excision Repair (NER) and Base Excision Repair (BER) is true? Only NER involves the action of DNA ligase to seal nicks in the DNA backbone. Both NER and BER involve DNA strand cleavage by an endonuclease. Both NER and BER can be activated by exposure to visible light. Only BER requires DNA polymerase. Both NER and BER involve the creation of an apyrimidinic (AP) site.arrow_forward
- A strain of Neisseria gonorrheae has recently acquired the ability to be resistant to the antibiotic penicillin. Evidence indicates that this is not a new mutation but rather a gene received from another bacterium. After the new genetic information recombines with the genome, how would gonorrheae use the DNA to resist the action of penicillin? The gene would be transcribed into RNA and then translated into protein. The gene would translated into protein and then transcribed into RNA. The gene would be recognized as a mutation and repaired. The gene would be released from the N. gonorrheae as naked DNA.arrow_forwardDuring high stress environments, it has been found that some bacteria activate a genetic mechanism that allows them to incorporate more mutations into the DNA during replication. Would the following two enzymes be impacted by such a mechanism? In each case, provide a reason for your answer. i) DNA polymerase III ii) Helicasearrow_forwardBased on what you have learned with respect to various DNA repair pathways, decide the most appropriate pathway that would be used to repair the following types of DNA damage. Explain your reasoning. A change in the DNA sequence caused by a mistake made by DNA polymerase during replication In a fungal species, pyrimidine dimers induced as a result of UV exposure A double-stranded break that occurs during G1 and prevents completion of DNA replicationarrow_forward
- Explain the following statement : a) initiation of bacteriall DNA replication is an energy requiring process b) bacterial DNA polymerase can enter the termination sequence but cannot exisarrow_forwardWhich of the followings statements are true about DNA polymerase? 1.) It can only go in one direction, meaning the lagging strand can't be synthesized continuously. 2.) It cannot start a DNA strand from scratch, so another enzyme is needed to create "primers" as a starting point. 3.) It cannot copy epigenetic marks (such as methyl groups) on its own; these must be "copied" onto the daughter DNA strand by other enzymes after DNA replication. 4.) All of the abovearrow_forwardYou examine DNA replication in an E. coli mutant, which has a partially defective DNA polymerase. In vitro experiments using the mutant DNA polymerase gives an error rate of 10-3, as compared to the expected error rate of 10-6. Which of the following activities is the mutant polymerase likely to be missing, as compared to the normal polymerase? Explain your answer.arrow_forward
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