Anatomy & Physiology
1st Edition
ISBN: 9781938168130
Author: Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher: OpenStax College
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Chapter 12, Problem 5ILQ
What happens across the membrane of an electrically active cell is a dynamic process that is hard to visualize with static images or through text descriptions. View this animation (http://openstaxcollege.org/l/dynamic1) to really understand the process. What is the difference between the driving force for Na+ and K+? And what is similar about the movement of these two ions?
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What happens across the membrane of an electrically active cell is a dynamic process that is hard to visualize with static images or through text descriptions. View this animation (http://openstaxcollege.org/l/dynamic1) to learn more about this process. What is the difference between the driving force for Na+ and K+? And what is similar about the movement of these two ions?
What happens across the membrane of an electricallyactive cell is a dynamic process that is hard to visualizewith static images or through text descriptions. View thisanimation (http://openstaxcollege.org/l/dynamic1) toreally understand the process. What is the differencebetween the driving force for Na+ and K+? And what issimilar about the movement of these two ions?
Hyperkalemia is a condition by which ECF potassium levels become too high (usually due to kidney failure). Consider the following questions about the consequence of hyperkalemia on membrane potential.
How would hyperkalemia affect EK?
Considering your answer to the previous question, how would hyperkalemia affect membrane potential?
Chapter 12 Solutions
Anatomy & Physiology
Ch. 12 - In 2003, the Nobel Prize in Physiology or Medicine...Ch. 12 - Visit this site...Ch. 12 - Visit this site...Ch. 12 - View the University of Michigan Webscope...Ch. 12 - What happens across the membrane of an...Ch. 12 - Visit this site...Ch. 12 - Watch this video...Ch. 12 - Watch this video...Ch. 12 - Which of the following cavities contains a...Ch. 12 - Which structure predominates in the white matter...
Ch. 12 - Which part of a neuron transmits an electrical...Ch. 12 - Which term describes a bundle of axons in the...Ch. 12 - Which functional division of the nervous system...Ch. 12 - What type of glial cell provides myelin for the...Ch. 12 - Which part of a neuron contains the nucleus?...Ch. 12 - Which of the following substances is least able to...Ch. 12 - What type of glial cell is the resident macrophage...Ch. 12 - What two types of macromolecules are the main...Ch. 12 - If a thermoreceptor is sensitive to temperature...Ch. 12 - Which of these locations is where the greatest...Ch. 12 - How long does all the signaling through the...Ch. 12 - What is the target of an upper motor neuron?...Ch. 12 - What ion enters a neuron causing depolarization of...Ch. 12 - Voltage-gated Na+ channels open upon leaching what...Ch. 12 - What does a ligand-gated channel require in order...Ch. 12 - What does a mechanically gated channel respond to?...Ch. 12 - Which of the following voltages would most likely...Ch. 12 - Which of the following is probably going to...Ch. 12 - How much of a change in the membrane potential is...Ch. 12 - A channel opens on a postsynaptic membrane that...Ch. 12 - What neurotransmitter is released at the...Ch. 12 - What type of receptor requires an effector protein...Ch. 12 - Which of the following neurotransmitters is...Ch. 12 - What responses are generated by the nervous system...Ch. 12 - When eating food, what anatomical and functional...Ch. 12 - Multiple sclerosis is a demyelinating disease...Ch. 12 - Which type of neuron, based on its shape, is best...Ch. 12 - Sensory fibers, or pathways, are referred to as...Ch. 12 - If a person has a motor disorder and cannot move...Ch. 12 - What does it mean for an action potential to be an...Ch. 12 - The conscious perception of pain is often delayed...Ch. 12 - If a postsynaptic cell has synapses from five...Ch. 12 - Why is the receptor the important element...
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- The normal concentrations for intracellular and extracellular potassium in a neuron are [K+]in = 150 mM and [K+]out = 5 mM, respectively. Due to an electrolyte imbalance, a patient has the following intracellular and extracellular concentrations of potassium: [K+]in = 140 mM and [K+]out =2 mM. Using the Nernst equation (Chapter 4), calculate the equilibrium potential for potassium in the cells with normal K+ distributions and of the diseased patient. Refer back to Question #1. Will it be easier or more difficult to generate an action potential in the diseased neuron as compared to the normal neuron? Why?arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 27 mM at 20 ∘C ? Please answer asap and in short and content should not be palgarised pleasearrow_forwardMembrane potential in cells is constantly fluctuating. These fluctuations are called graded potentials and we will learn more about them in future lectures. Look at the fluctuating graded potential in the graph as an example. If Cl- generally has a relatively low membrane permeability, how would increasing Cl- permeability affect this graph?arrow_forward
- Fill in the diagram, your illustration should demonstrate for each phase of the AP: 1. The relative concentration of K and Na 2. The relative voltage across the membrane 3. Any movement across the membrane of K and NA 4. The three kinds of channels in the membrane, and their state (open or closed) 5. Finally, indicate on the graph of the AP which phases correspond to hyper- polarization and which phases correspond to de- polarization Outside Outside Inside Inside Outside Inside Outside 1 Outside Inside Insidearrow_forwardWhich of the following intracellular potentials would have the greatest electrical attraction for Na+ to enter the cell? -70mV Ⓒ) -100mV -50mV OmV +20mVarrow_forwardIf a cell with the following ion concentrations had a resting membrane potential of -40mV which of the following can you conclude? Extracellular: Cl- = 110 mM, Na+ = 145 mM, K+ = 5mM. Intracellular Cl- = 20 mM, Na+ = 10 mM, K+ = 140mM a) At rest it is only permeable to potassium b) At rest it has some permeability to more than one of these ions c) At rest it is only permeable to chloride d) Rest it is not permeable to sodiumarrow_forward
- Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item (a, b, c, or d) best represents the forces and fluxes for a membrane potential of +20 mV? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.arrow_forwarddescribe what the resting membrane potential of a cell is. What is the resting membrane potential of neurons (give units)? What are the two factors that generate the resting membrane potential? Think of scenarios that change the factors that generate the resting membrane potential and how that would change the overall resting membrane potential.arrow_forwardWhat is the equilibrium membrane potential due to Na+ ions if the extracellular concentration of Na+ ions is 154 mM and the intracellular concentration of Na+ ions is 23 mM at 20 ∘C ?arrow_forward
- Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -40 mV (a, b, c, or d)? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.arrow_forwardA resting cell's membrane is more permeable to K+ simply because: K has a higher atomic number than Na. The Na+/K+ ATPase only works in response to a stimulus. There are more voltage-gated K+ channels than voltage-gated Na+ channels in the cell membrane. There are more K+ leaky channels than Na+ leaky channels in the cell membrane.arrow_forwardIn the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential. Discuss the importance of threshold. How does this relate to the concept of APs being all or none?arrow_forward
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