
(a) Interpretation:
The balanced equation for the reaction catalyzed by PFK-2 should be written.
Concept Introduction:
PFK-2 is an enzyme that indirectly regulates the glycolysis rate in the cells. It is known to be a bifunctional enzyme due to its structure. The two domains independently act as functional enzymes because both are located on one protein honodimer.
In mammals, different PFK-2 isoforms are encoded by genetic mechanisms to accommodate tissue specific needs. General function of PFK-2 remains the same. Slight differences in enzymatic properties are featured by isoforms which are then controlled by different methods of regulation.
(b) Interpretation:
The balanced equation for the conversion of 2 moles of oxaloacetate to glucose should be written.
Concept Introduction:
Gluconeogenesis is a
(c) Interpretation:
The balanced equation for the conversion of glucose to UDP-Glc should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combined with a phosphate to form ATP, the reaction is as follows:
(d) Interpretation:
The balanced equation for the conversion of 2 moles of glycerol to glucose should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combine with a phosphate to form ATP, the reaction is as follows:
Also, NAD+ is an oxidizing agent as it accepts electrons from other molecules to get reduced to NADH. Here, NADH can act as a reducing agent to donate electrons. Thus, the main function of NAD is electron transfer reaction.
(e) Interpretation:
The balanced equation for the conversion of 2 moles of malate to glucose-6-phosphate should be written.
Concept Introduction:
ATP to ADP conversion is reduction reaction. Energy released from the hydrolysis of ATP to ADP, this energy is used in cellular processes. Also, ADP can combine with a phosphate to form ATP, the reaction is as follows:
Similarly, the conversion of GTP to GDP is also a reduction reaction.

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Chapter 12 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
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