(a) Interpretation:
The statement "In liver, glucagon stimulates glycogen breakdown via camp. Although you might expect glucagon to stimulate catabolism of the glucose formed as well, glucagon inhibits glycolysis and stimulates gluconeogenesis in liver" should be explained.
Concept introduction:
When there is glycogen breakdown under the influence of glycogen, it releases glucose. Enzyme glucose -6-phosphate is essential for the formation of glucose by liver which it transports to other tissues. Phosphorylase kinase is an enzyme that donates phosphorous to convert the phosphorylase b (inactive) to a (active).
(b) Interpretation:
The statement "an individual with glucose − 6- phosphate deficiency suffers from chronic hypoglycemia" should be explained.
(c) Interpretation:
The statement "the action of phosphorylase kinase simultaneously activates glycogen breakdown and inhibits glycogen synthesis" should be explained.
(d) Interpretation:
The statement "the presence in liver of glucose-6-phosphate is essential to the function of the liver in synthesizing glucose for use by other tissues" should be explained.
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Biochemistry: Concepts and Connections (2nd Edition)
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