Chapter 12, Problem 23P

Interpretation Introduction

Interpretation:

To sketch curves relating to glycogen synthase reaction velocity to [UDP-glucose] for both a and b forms of the enzyme in the presence and absence of glucose-6-phosphate.

Concept introduction:

Glycogen synthase enzyme catalyzes the rate-limiting reaction step in glycogen synthesis in the liver as well as in skeletal muscles by transferring glucose monomers from UDP-glucose to the terminal end of the growing chain of glycogen by the formation of $\alpha \text{(1}\to \text{4)}$ glycosidic bonds.