Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 12, Problem 32P
Interpretation Introduction

Interpretation:

Side reaction mechanism for erythrose-4-phosphate to 4-phospho-erythronate should be identified.

Concept introduction:

Enzymes are the metabolic proteins which help in catalyzing a substrate to the product at a fast rate and it is specific, which indicates that the particular enzyme belongs to a particular substrate. They also catalyze side reactions but at slower rates. The oxidative phosphorylation of glyceraldehyde-3-phosphate takes place with the help ofGAPDH to pyruvate. This GAPDH slowly convertserythrose-4-phosphate to 4-phospho-erythronate which is a side reaction.

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