To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride. Concept introduction: The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

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Answer 1

Question

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

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Propose a mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Answer 2

Question

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

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Answer 3

Question

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

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Answer 4

Question

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

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Answer 5

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

Answer 6

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

Answer 7

Chapter 11.14, Problem 27P

Interpretation Introduction

Interpretation:

To write the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

Concept introduction:

The reaction of an acyl chloride with acetate ion is a nucleophilic substitution reaction. The acetate ion acts as a nucleophile and attacks the carbonyl carbon of the acyl chloride. The attack results in the formation of a tetrahedral intermediate. Some chloride group attached to the carbonyl carbon acts as a leaving group in the reaction and results in the collapse of the tetrahedral intermediate to form the corresponding anhydride.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 11.1 - The aromas of many flowers and fruits are due to...Ch. 11.1 - Name the following compounds:Ch. 11.1 - Prob. 3P Ch. 11.2 - Prob. 4P Ch. 11.2 - Prob. 5P Ch. 11.4 - a. What is the product of the reaction of acetyl...Ch. 11.4 - Prob. 7P Ch. 11.5 - Using the pKa values listed in Table 11.1, predict...Ch. 11.6 - Starting with acetyl chloride, what neutral...Ch. 11.6 - Prob. 10P

Solution Summary: The author explains the mechanism for the reaction of an acyl chloride with acetate ion to form an acid anhydride.

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