Essential Organic Chemistry, Global Edition
Essential Organic Chemistry, Global Edition
3rd Edition
ISBN: 9781292089034
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Chapter 11.12, Problem 22P
Interpretation Introduction

Interpretation:

The mechanism has to be written for the reaction of an amide with an alcohol in presence of an acid catalyst to give ester as a product.

Concept introduction:

The general reaction of an amide with an alcohol does not give a product. As amides are least reactive carboxylic acid derivatives so to increase the reactivity of amides a mineral acid is added. Thus reaction of alcohol and amides in presence of acid gives an ester as a product. The reaction eqaution is written as,

Essential Organic Chemistry, Global Edition, Chapter 11.12, Problem 22P

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