Chapter 10, Problem 4CHI

Summary Introduction

To develop: A model whereby BrnQ transports valine and the observed growth inhibition in Chlamydia is due to competitive inhibition by high levels of four growth inhibitory amino acids (methionine, leucine, phenylalanine, and isoleucine).

Introduction: Chlamydia depends on the host for its nutrients such as lipids, nucleotides, and amino acids and thus can only grow inside a eukaryotic host cell. Thus, in the case of depletion of any of these nutrients, the growth of Chlamydia declines.