Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 10, Problem 44FB
Summary Introduction

To review:

The blank space in the statement, “The major enzymatic defense against oxidative stress is provided by superoxide dismutase, glutathione peroxidase, peroxiredoxin, and __________.”

Introduction:

Oxidative stress is the condition when the production of free radicals and antioxidant mechanisms, to detoxify their damaging effects, are imbalanced. Under such conditions, the levels of reactive oxygen species (ROS) rise and may result in some damage. ROS includes hydrogen peroxide, singlet oxygen, superoxide radical, and hydroxyl radical.

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Two tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu  Gly-Asp-Asp-Leu  Can you please help show the titration curve for both of these peptides and calculate the PI?
Two tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu  Gly-Asp-Asp-Leu  What is the structure of the PTH derivative produced during the last round of amino acid sequencing?
What is the primary sequence of this undecapeptide? Also,   if x-ray crystallography shows a highly stable hairpin turn within the polypeptide, what about the primary sequence explains this structural feature?
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