Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 10, Problem 2Q
Summary Introduction

To review:

The way DNP (dinitrophenol) consumption led to weight loss and caused deaths due to liver failure in the 1920s when people utilized it as a dietary aide.

Introduction:

Oxidative phosphorylationthat occurs in the mitochondria is a metabolic pathway that produces energy in the form of ATP (adenosine triphosphate) by establishing a proton gradient. This proton gradient, across the membrane, is produced by the transfer of electrons through four complexes that are found embedded within the inner membrane. Lastly, ATP synthase enzyme that is present in tandem with these complexes produces ATP by utilizing this proton gradient.

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