Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Dosage compensation is critical for organisms with sex chromosomes to equilibrate gene expression. The role of long non-coding RNAs has been shown to play an important role in affecting the decision to carry out X chromosome inactivation during dosage compensation in mammals.
Q9a) How can a long non-coding RNA affect the decision to keep an X-chromosome active in female mammals?
Q9b) How can a long non-coding RNA initiate the steps to silence the chromosome to be inactivated?
Q9c) Explain which long non-coding RNA is responsible for the various steps to silence the inactive X and describe how its function leads to changes in the chromatin that are incompatible with active transcription off the inactive X
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