ow does DNA methylation occur? What enzyme is involved in DNA methylation? What are the consequences of DNA methylation? What is base flipping and why is it significant? How do bacteria use methylation to protect their own DNA? How is methylation is used to silence genes in plants and mammals? What is epigenetic silencing? How is DNA methylation involved in X-chromosome inactivation and genomic imprinting in mammals?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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  1. ow does DNA methylation occur?
    • What enzyme is involved in DNA methylation?
    • What are the consequences of DNA methylation?
    • What is base flipping and why is it significant?
    • How do bacteria use methylation to protect their own DNA?
    • How is methylation is used to silence genes in plants and mammals?
    • What is epigenetic silencing?
    • How is DNA methylation involved in X-chromosome inactivation and genomic imprinting in mammals?
  2. What are boundary elements and what role do they play in separating chromatin domains?
    • How do special DNA sites facilitate the transition between euchromatin and heterochromatin?
    • How do boundary elements affect chromatin modification?
    • How do boundary elements function by binding specific proteins?
  3. What are the elements required for chromosome function?
    • List the specialized regions that direct essential chromosomal functions.
    • How does the “origin” site initiate DNA replication?
    • Why is a replication of linear DNA more complicated than the replication of circular DNA?
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