Match each factor involved in miRNA biogenesis with its function , pri-miRNA forms a hairpin that is recognized by Drosha and DGCRS A. , Drosha and DGCRS B cleave non-complementary tails off pri-miRNAS exportin 5 c transfers pre-miRNA from the nucleus to the cytoplasm , Dicer D. processes pre-MIRNAS into mature 20-25 nt miRNAS RISC binds to MRNAS and represses their translation or targets them for degradation

Q: An ncRNA may have the following functions: scaffold, guide,alterer of protein function or stability,…

A: ncRNA or non-coding RNAs, as the name suggests, are RNA molecules which do not code for…

Q: A particular mature miRNA (microRNA) in mice has sequence 5'-UUCCCUGAGACCUCAAGUGUGA-3'. a. If you…

A: Answer a) ii and iii ii) mRNA sequence complementary to the miRNA sequence iii) miRNA sequence with…

Q: The piRNA, miRNA and RNAi pathways are all similar and may have evolved from some early function of…

A: Both microRNA (miRNA) and RNA interference (RNAi) pathways has an enzyme called DICER(RNAse III…

Q: The RNA-induced silencing complex (RISC) _____ i. Binds to and unwinds ds siRNA/miRNA to produce…

A: The answet is b. II only RNA-induced silencing complex(RISC) is a multiprotein complex which…

Q: How do the changed bases contribute to the 3dimensional structure and function of the TTRNA?

A: To find: How the changes in bases contribute to 3D structure of TTRNA. and function of TTRNA.

Q: Describe the function in prokaryotic transcription of theRNA polymerase core enzyme, sigma (σ)…

A: The first step in gene expression is the transcription, which is a common phenomenon in both…

Q: miRNAS P. are synthesized as long pri-miRNAs (up to 1000 nucleotides). Q. are transcribed by RNA…

A: Micro RNAs are found in animals, plants and some viruses. These are single stranded RNA molecule…

Q: MicroRNA (miRNA) in eukaryotes are similar to anti-sense RNA in bacteria in that they regulate…

A: RNA is one of the three principal biological macromolecules required for all well-known life forms…

Q: Do you think it would be easier to mutate the GR receptor or treat someone with a miRNA to overcome…

A: MicroRNAs are a grade of non-coding RNAs which plays vital role in managing gene expression. Large…

Q: 1.The two proteins which START the poly-adenylation process in mRNAs are: CPSF and PAP CPSF and…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Let’s suppose that the overexpression of a particular miRNA was associatedwith pancreatic cancer.…

A: Answer is b.) A DNA -demethylating agent .

Q: Which of the following is NOT true of miRNAs?   A. Pri-miRNAs are processed by Drosha in the…

A: A microRNA, also known as a miRNA, is a single-stranded, non-coding RNA molecule that is very small.…

Q: In the figure below, what is represented by the line labeled A? TFIIB recognition element DNA in m…

A: Transcription of genes includes the formation of RNA using the template DNA. It includes the enzyme…

Q: Mechanistic analysis of silencing mechanisms showed that exogenous double-stranded RNA was processed…

A: We know that RNA interference is a conserved mechanism of gene regulation that is induced by small…

Q: Diagram the fate of the dsRNA once it enters a cell, highlighting the enzymatic reactions that…

A: RNAi is a biological molecular process, where dsRNA molecules perform the sequence specific…

Q: An ncRNA may have the following functions: scaffold, guide, alterer of protein function or…

A: Introduction  RNA stands for Ribose Nucleic Acid; it also serves as genetic material in many species…

Q: In table 21.1, the effects of injection of different types of RNA into wild type mice was examined.…

A: miRNA(micro RNA) is type of non coding, single strand RNA. It involves in gene silencing and…

Q: Complete the table to figure out if transcription is happening or not.   Glucose Lactose LacI…

A: Operons are a combination of genes that function together to regulate the transcription of…

Q: Xist is an example of an lcnRNA responsible for X-inactivation. Describe its biogenesis, and decide…

A: Chromosome-based sex determination systems create an imbalance  in the dosage of X-linked genes…

Q: The RNA-induced silencing complex (RISC) I. binds to and unwinds ds siRNA/MIRNA to produce ss…

A:

Q: 17 Addition of the transcription factors KIf4, Sox2 and Oct4 to a fully differentiated cell, leads…

A: Cell potency is the ability of the cell to differentiate into different cell types. Similarly, stem…

Q: RNA processing events include A. self splicing B. methylation of 45S FRNA C. snoRNA facilitates…

A: Introduction: RNA processing involves newly transcribed RNA molecules (primary transcript)…

Q: How is the splicing of U2-dependent introns different from that of U12-dependent introns? O a.…

A: The non-coding sequences are called introns and hence are needed to be removed from RNA. This is…

Q: TAATTGE IGGAG anog regulatory sequence en this interaction map which DNA sequence would the…

A: Transcription regulation is a mechanism in which gene expression is regulated. For this purpose…

Q: Which mechanisms are used by miRNAs to regulate expression? O Targeted degradation of mRNAs O…

A: Introduction: MicroRNAs (miRNAs) are non-coding endogenous single-stranded RNAs that play an…

Q: Provide the SIGNIFICANT differences between the following: 1. Regulation AFTER transcription mRNA…

A: The process of mRNA processing involves the removal of the intron sequences and the joining together…

Q: What is the correct order of events during transcription Group of answer choices a. Initiation,…

A: Transcription is the process in which the mRNA is formed from the DNA by the process of…

Q: Select all the correct types of RNA that are both the product of transcription and are also…

A: RNA plays a very important role in biological processes and also acts as Genetic material in some…

Q: MicroRNA hsa-miR-155-5p targets mRNA that encode the genes JARID2 and KDM5B. In the cells of some…

A: MicroRNAs are small non coding RNA molecules that can regulate gene expression by binding to the…

Q: The phosphorylation of the RNA polymerase II tail is important for the following EXCEPT a.the…

A: Among many subunits, the largest subunit of RNA polymerase 2 (RBP1) has a long carboxy-terminal tail…

Q: Nascent form of the mRNA  A. undergoes splicing only after capping B. is also called hnRNA C. is…

A: A. undergoes splicing only after capping B. is also called hnRNA D. participates in the spliceosome…

Q: microRNAs (miRNAs) play important roles in gene regulation. What is the correct order of steps…

A: A class of short, endogenous RNAs with a length of 21–25 nucleotides (nts) is known as microRNAs…

Q: The trp operon is: **(for additional information review the CogBooks Module, answer explained on…

A: Negative inducible operons is a method wherever the active regulator macromolecule binds to the…

Q: . Based on this information, which of the following statements would be supported by these results?…

A: BRCA1  It is a human tumor suppressor gene and suppress the growth of tumor cells.

Q: onsidering the 7 levels of gene regulation, which of the following mechanisms acts at first level?…

A: Gene expression is a tedious process involving several steps such as replication, transcription and…

Q: In vitro translation systems have been developed inwhich specific RNA molecules can be added to a…

A: DNA (deoxyribonucleic acid) is first transcribed to form mRNA (messenger ribonucleic acid) which is…

Q: When dsRNA is treated with Dicer enzyme siRNA and miRNA’s are produced. What role they will play in…

A: siRNA is a type of double stranded short sequence rna which is non coding and take part in RNA…

Q: The U1 splice donor site is critical for positioning of the U1snRNP for appropriate splicing. What…

A: U1 snRNP (Small Nuclear Ribonucleoprotein Particle):The U1 snRNP is a component of the spliceosome,…

Q: a) Tryptophan-repressor complex binds to operator     Gene is switched ON     Gene is switched OFF…

A: The tryptophan operon , required for the synthesis of the amino acid tryptophan, is an example of a…

Q: Each set cosists of five key players in the processes involved in the central dogma. Choose only two…

A: One of the central dogmas of molecular biology is that genetic information passes from nucleic acids…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.