A particular mature miRNA (microRNA) in mice has sequence 5'-UUCCCUGAGACCUCAAGUGUGA-3'.a. If you wanted to predict which mouse mRNAs are regulated by this miRNA, what would you lookfor? Choose one or more.i. mRNA sequence the same as the miRNA sequenceii. mRNA sequence complementary to the miRNA sequenceiii. mRNA sequence including a RISC binding siteiv.mRNA sequence including 5'-CUCAGGGAA-3'v. mRNA sequence including 5'-UUCCCUGAG-3'b. Your sequence analysis predicts that 200 mRNAs may be targets of this miRNA. You engineermouse cells that produce an excess of this miRNA. For the real targets, we predict thatin these cells over-expressing the miRNA, compared to the unmodified cells.Choose one or more, and explain.i. The target gene is deleted in cells with an excess of the miRNAii.The target is translated less in cells with an excess of the miRNAiii. The target is translated more in cells with an excess of the miRNAiv. There is more of the target mRNA in cells with an excess of the miRNAv.There is less of the protein product of the target mRNA in cells with an excess ofthe miRNAC.vi.There is more of the protein product of the target mRNA in cells with an excessof the miRNAWould you expect to find one or many mRNAs that are genuinely regulated by the miRNA?OneMany

Name: A particular mature miRNA (microRNA) in mice has sequence 5'-UUCCCUGA
Uploaded: 2024-03-20T06:42:41.000Z
Channel: Bartleby
Description: A particular mature miRNA (microRNA) in mice has sequence 5'-UUCCCUGAGACCUCAAGUGUGA-3'.a. If you wanted to predict which mouse mRNAs are regulated by this miRNA, what would you lookfor? Choose one or more.i. mRNA sequence the same as the miRNA seque