microRNAs (miRNAs) play important roles in gene regulation. What is the correct order of steps (using letters A - E) for miRNA biogenesis or formation? A. Synthesis of pri-miRNA B. Targeting of mRNA for translation repression or mRNA degradation C. Loading into RISC complex D. Formation of mature miRNA E. Formation of pre-miRNA ACBDE CDAEB O ECABD ADCEB O AECDB

microRNAs (miRNAs) play important roles in gene regulation. What is the correct order of steps (using letters A - E) for miRNA biogenesis or formation? A. Synthesis of pri-miRNA B. Targeting of mRNA for translation repression or mRNA degradation C. Loading into RISC complex D. Formation of mature miRNA E. Formation of pre-miRNA ACBDE CDAEB O ECABD ADCEB O AECDB

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Description: Give typing answer with explanation and conclusion microRNAs (miRNAs) play important roles in gene regulation.What is the correct order of steps (using letters A - E) for miRNAbiogenesis or formation?A. Synthesis of pri-miRNAB. Targeting of mRNA for

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter16: Regulation Of Gene Expression

Section: Chapter Questions

Problem 7TYK

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Match the following list of RNAs (left side) with their function(s) (right side).w. mRNA i. block translation of elected mRNAsx. rRNA ii. modification and processing of rRNAy. snoRNA iii. modification of snoRNA and snRNAz. snRNA iv. components of ribosomeaa. tRNA v. spilicing of RNA transcriptsbb. scaRNA vi. directs degradation of selected mRNAscc. miRNA vii. codes for proteinsdd. siRNA viii. adaptor for protein synthesis
Which mechanisms are used by miRNAs to regulate gene expression? O Targeted degradation of mRNAs O Targeted inhibition of mRNA translation O Both A and B ONeither A nor B
Which one of the following isare true regarding the endogenous (made in the cell) miRNA a. They play a role in regulating the gene expression Ob. All statements are true O C. Only B&C are true d. miRNA genes encode them е. They have a loop-like structure The phrase GỌI cloned downstream of promoter in plasmid cloning means O a. GOI cloned before the promoter. O b. GOI cloned after the multiple cloning sites. O c. GOI cloned after the origin of replication. d. GOI cloned after the promoter. GỌI cloned inside the promoter sequence. е. Nucleotide misincorporation usually takes place during a. Replication b. Transformation Oc. High fidelity PCR d. Transposon insertion O e. Translation O O
Do you think it would be easier to mutate the GR receptor or treat someone with a miRNA to overcome the negative aspects of the stress response? Why?
Match the following list of RNAs (left side) with their function(s) (right side). mRNA i. block translation of elected mRNAs rRNA ii. modification and processing of rRNA snoRNA iii. modification of snoRNA and snRNA snRNA iv. components of ribosome tRNA v. spilicing of RNA transcripts scaRNA vi. directs degradation of selected mRNAs miRNA vii. codes for proteins siRNA viii. adaptor for protein synthesis (
Explain how the miR-200 family of miRNAs behave as tumorsuppressorgenes. What happens when their expression is blocked or decreased?
What are the differences between miRNA and siRNA? (Select all that apply.) OmiRNAs carry the genetic information from the DNA in the nucleus directly to the cytoplasm, and siRNAs are involved in the degradation of specific mRNA molecules. miRNAs are from 22 to 30 bases long, and siRNAs are 22 bases long. O miRNAs carry the genetic information from the DNA in the nucleus directly to the cytoplasm, and siRNAs help with the processing of the initial mRNA transcribed from DNA into a mature form. miRNAs prevent translation of certain mRNAs, and siRNAs are involved in the degradation of specific mRNA molecules. miRNAs are 20 to 22 bases long, and siRNAs are from 20 to 30 bases long.
Match each of the following descriptions to the type of regulatory RNA affecting a "target" gene (aka, the gene the regulatory RNA is regulating). Use each answer once. This regulatory RNA may increase siRNA transcription of the target gene by recruiting activator proteins. secondary structures on RNA can become... IncRNA these regulatory RNAs regulate gene miRNA expression post transcriptionally generally by binding to the 3'-UTR regions of their target RNAs > >
What is the order of the tRNA binding sites on the 70S ribosome with respect to the 5'→ 3' direction of mRNA? O a. PAE ОБ.ЕРА OC. AEP O d. PEA O e. E AP Which of the following is TRUE regarding eukaryotic RNA processing? O a. Functional individual FRNA cannot be produced without splicing. O b. Splicing of the MRNA precursor is done in the cytoplasm, while modification of the ends is done in the nucleus. OC. An unprocessed mRNA precursor is translocated into the cytoplasm to be modified before the translation. O d. Splicing of the mRNA precursor is done in the nucleus, while modification of the ends is done in the cytoplasm. O e. Transcription yields primary transcript, which can by itself yield a functional protein. RNA self-splicing demonstrates the role of RNA as a(n): O a. spliceosome. O b. intron. O c. nucleophile. O d. exon. O e. catalyst.
CTA GCC CTC CGT TAC TAG TTA CCT ACT TAT TCA ATT TTG TAA ACG CTC ATC CGA ACC CGC TTT TAA TTG CCC ACT TAG TCG ATT ACC CGT TTA TGT TAA TTA CCT ATC 1. Build the mRNA molecule matching the RNA nucleotides to the DNA nucleotides properly letter by letter. (assume that the mRNA is bacterial there are not intros to cut out) 2. Figure out the tRNA triplet (codons) that would fit the mRNA triplets. (letter by letter) 3. Look up for each tRNA codon and find the corresponding symbol and amino acid abbreviations. The symbols should spell out a meaningful English message.
O File C:/Users/Admin/Downloads/cbcc9-guided-reading-ch11.pdf o Sign Off o Outlook O New Tab eE broccoli 0/0 2国《 reading-ch11.pdf 會 %00L 14. Complete the following table, which compares late-stage gene regulation mechanisms. MRNA breakdown Initiation of translation Protein processing Description Example
For each item in the left column, enter in the indicated space the best match from the right column. Right Column Match A group of proteins that promote gene silencing by including specific siRNAS and/or miRNAS A. Pasha (partner of Drosha) B. let-7 (miRNA) It converts primary miRNAs (pri-MİRNA) into precursor miRNAS (pre-miRNAS) for miRNA maturation C. RISC (complex) It is a gene whose transcript is targeted for degradation when it is bound by miRNAS D. lin-4 (MRNA) It is processed by Dicer after exogenous dsRNAS, were injected (typically not encoded in an organism's genome) E. SİRNA (short interfering RNA) It is processed from a pri-miRNA expressed by the cell and binds to MRNAS of other genes to promote their degradation F. HRDE-1 (Argonaute) It directs gene-silencing in germ cells leading to multigenerational RNAI inheritance