Leptin was first discovered in a strain of mice (called ob mice). These mice have a genetic mutation that causes them to be obese. What was found to be the underlying cause of their obesity? Ob mice were injected with the hormone leptin which caused decreased metabolism, overeating and obesity. The ob mice had high amounts of leptin in their fat cells causing decreased metabolism and overeating. The fat cells in ob mice did not produce leptin causing decreased metabolism and overeating. Ob mice have increased satiety signals as a result of increased leptin levels.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Leptin was first discovered in a strain of mice (called ob mice). These mice have a genetic mutation
that causes them to be obese. What was found to be the underlying cause of their obesity?
Ob mice were injected with the hormone leptin which caused decreased metabolism, overeating and
obesity.
The ob mice had high amounts of leptin in their fat cells causing decreased metabolism and overeating.
The fat cells in ob mice did not produce leptin causing decreased metabolism and overeating.
Ob mice have increased satiety signals as a result of increased leptin levels.
Transcribed Image Text:Leptin was first discovered in a strain of mice (called ob mice). These mice have a genetic mutation that causes them to be obese. What was found to be the underlying cause of their obesity? Ob mice were injected with the hormone leptin which caused decreased metabolism, overeating and obesity. The ob mice had high amounts of leptin in their fat cells causing decreased metabolism and overeating. The fat cells in ob mice did not produce leptin causing decreased metabolism and overeating. Ob mice have increased satiety signals as a result of increased leptin levels.
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