Which of the following does not correctly describe the isozymes of lactate dehydrogenase (LDH)in skeletal muscle and heart muscle?the B4 isozyme of LDH is the main enzyme form in heart musclethe A and B subunits of LDH are encoded by the same gene and have identical amino acid sequencesO lactic acid is used as a fuel by the B4 isozyme to produce cellular energyO the A4 isozyme of LDH is the main form in skeletal muscleO lactic acid is produced by the A4 isozyme during active exercise

Lactate dehydrogenase (LDH) is an enzyme which catalyzes the conversion of lactate to pyruvate along…

Answered: Which of the following does not…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

Which amino acids can be converted to pyruvate by a single enzyme-catalyzed reaction?
Name four amino acids that can be converted directly (in one step) into pyruvate or a citric acid cycle intermediate, and name the intermediate formed from each.
The citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in red). Identify which of the carbons in each intermediate will be labeled in the first round of the cycle by selecting the indicated carbon(s). Each question has multiple options, please choose more than one. Which carbon(s) in α‑ketoglutarate will contain C14? 1 2 3 4 5 Which carbon(s) in succinyl‑CoA will contain C14? 1 2 3 4 Which carbon(s) in succinate will contain C14? 1 2 3 4 Which carbon(s) in fumarate will contain C14? 1 2 3 4 Which carbon(s) in malate will contain C14? 1 2 3 4 Which carbon(s) in oxaloacetate will contain C14? 1 2 3 4
Strategies for regulating the central pathways in carbohydrate metabolism vary among different cells in one organism and among organisms. Slight changes in the regulation of enzymes in central metabolism can effectively re-route metabolite traffic through these pathways, just like a small mutation in PFK-1 can convert a healthy cell into a cancerous one. For instance, Gillaspera mold uses an alternative strategy for regulation the TCA and glycolysis. Gillaspera contains a unique isocitrate dehydrogenase that has an allosteric site for citrate. High citrate inhibits isocitrate dehydrogenase in this organism. Gillaspera also lacks a citrate binding site on PFK-1, so this variant of the enzyme is not affected by citrate concentrations at all. Gillaspera lacks the enzymes ethanol dehydrogenase and lactate dehydrogenase and no carbons are lost in its unique fermentation product. Would high glucose in these organisms lead to production of carbon dioxide from glucose catabolism?…
What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and a-ketoglutarate dehydrogenase?
Can you please pick the right answer in each parentheses (a) to (e)? Coenzymes are nonprotein compounds that are required for the activity of certain enzymes. One critical coenzyme central to metabolism is NAD+. In fact it is one of 5 coenzymes required by (a)< "pyruvate dehyrogenase" vs "citrate synthase" > , the critical enzyme for producing Acetyl-CoA. NAD+ is synthesized from (b)< "niacin (vitamin B3)" vs "acetate" > as was discovered to be critical for health by two American scientists, (c)<"Joseph Goldberger and Conrad Elvehjem" vs "Linus Pauling and Eric Lander"> , in the early 20th century. Dietary lack of this critical molecule produces pellagra, characterized by the following symptoms: (d)<"skin inflammation, dementia, diarrhea" vs "chorea-like movement">. People with these problems were found in parts of the U.S. where diets lacked vegetables and consisted principally of corn. Interestingly, soaking the corn in (e)<"salt water" vs…
Malate dehydrogenase is an enzyme that converts malate to oxaloacetate in the last stage of the TCA Cycle (citric acid cycle/Krebs cyde), represented by the following equation: NAD+ Malate Oxaloacetate NADH A group of students carried out an experiment to determine the optimum temperature for the activity of a commercially produced malate dehydrogenase (from yeast) at several different temperatures. A series of test tubes was set up containing 2.0 cm of phosphate buffer with a pH of 7.5, 0.1 cm? of NADH, 0.1 cm of malate dehydrogenase and 0.7 cm3 of water. The tubes were incubated in water baths at the various temperatures for 5 minutes. At certain time intervals each tube was placed in a colorimeter, set at an absorbance value of 1.0. The reaction was then started by adding 0.1 cm? of oxaloacetic acid to the tube. Enzyme activity was measured by following the decrease in absorbance for 120 seconds. The experiment was repeated to give duplicate results. Enzyme activity was then…
The pyruvate dehydrogenase complex catalyzes the synthesis of acetyl-CoA, a very important molecule in cellular metabolism. The reaction catalyzed by the pyruvate dehydrogenase enzyme complex is shown below. This reaction is tightly regulated, because it is essentially irreversible. Which of the following conditions is most likely to lead to the inhibition of pyruvate dehydrogenase in cells? (select two answers) High concentrations of acetyl-CoA High concentrations of pyruvate High concentrations of NADH High concentrations of NAD+ High concentrations of CoA
In own words, give 5 or more reasons why most of the clinical features of the diseases a-ketoglutarate dehydrogenase deficiency, succinate dehydrogenase deficiency, and fumarase deficiency involve muscle and nerve tissue? and explain those reasons.
a.) in human, under what condition will pyruvate be converted to lactate? what type of reaction occurs when pyruvate is converted to lactate? b.) in human, what happens to pyruvate when there is sufficient oxygen supply? which enzyme is involved in this chemical reaction?
Please describe four different modes of the regulation of the pentose phosphate pathway.
Please describe four different modes of the regulation of the pentose phosphate pathway.

SEE MORE QUESTIONS

Recommended textbooks for you

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781305961135

Author:

Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:

Cengage Learning

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Fundamentals of General, Organic, and Biological …

Biochemistry

ISBN:

9780134015187

Author:

John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson

Publisher:

PEARSON

SEE MORE TEXTBOOKS

Which of the following does not correctly describe the isozymes of lactate dehydrogenase (LDH) in skeletal muscle and heart muscle?