In a specific type of tumor, cytotoxic T cells can recognize but not kill the tumor cell. Interaction of PD-L1 in tumor cells with PD1 in cytotoxic T cells plays a role in shaping the immune response by initiating signal transduction cascades in both cell types. What will happen if the signal transduction cascade in cytotoxic T cells is blocked? T cells will be activated and kill tumor cells T cells can recognize the cancer cells but will not be activated Tumor cell will undergo programmed cell death
In a specific type of tumor, cytotoxic T cells can recognize but not kill the tumor cell. Interaction of PD-L1 in tumor cells with PD1 in cytotoxic T cells plays a role in shaping the immune response by initiating signal transduction cascades in both cell types. What will happen if the signal transduction cascade in cytotoxic T cells is blocked? T cells will be activated and kill tumor cells T cells can recognize the cancer cells but will not be activated Tumor cell will undergo programmed cell death
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter12: Body Defenses
Section: Chapter Questions
Problem 15RE
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In a specific type of tumor, cytotoxic T cells can recognize but not kill the tumor cell. Interaction of PD-L1 in tumor cells with PD1 in cytotoxic T cells plays a role in shaping the immune response by initiating signal transduction cascades in both cell types. What will happen if the signal transduction cascade in cytotoxic T cells is blocked?
T cells will be activated and kill tumor cells
T cells can recognize the cancer cells but will not be activated
Tumor cell will undergo programmed cell death
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