Individuals infected with herpes simplex virus (HSV) mount protective antibody responses directed against surface glycoproteins of the virus.   These antibodies are critical to viral clearance.  The act to neutralise any virus trying to infect a person’s cells as well as activating the classical pathway of complement and cytotoxic cell-mediated killing of infected target cells. Having a deficiency in the complement component C3 greatly impairs a person’s ability to control HSV infections.   To understand this further, you will investigate this in the lab.  Using C3-deficient mice, you infect them with HSV at day 0 and then a second time 4 weeks later.

Human Anatomy & Physiology (11th Edition)
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Individuals infected with herpes simplex virus (HSV) mount protective antibody responses directed against surface glycoproteins of the virus.

 

These antibodies are critical to viral clearance.  The act to neutralise any virus trying to infect a person’s cells as well as activating the classical pathway of complement and cytotoxic cell-mediated killing of infected target cells. Having a deficiency in the complement component C3 greatly impairs a person’s ability to control HSV infections.

 

To understand this further, you will investigate this in the lab.  Using C3-deficient mice, you infect them with HSV at day 0 and then a second time 4 weeks later.

 

 

 

 

 

A hypothesis is a tentative answer to a scientific question and is an important part of practical experiments.  A testable hypothesis is statement that can be proved or disproved as a result of experimentation.

 

Q1. State the problem that you are trying to solve. And then formulate a robust testable hypothesis for your scientific experiment.

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Transcribed Image Text:X Word File Edit View Insert Format Tools Table V US Reading List bartleby® 8 < G Add Image US Assignments: Combating Dise... learn Get live help whenever you need from online tutors! Try bartleby SEARCH LIBRARY 1,191 write W ||| Window Help bartleby.com EESubmit your question to our 24/7 subject matter experts with Masters and PhDs and get IMI A hypothesis is a tentative answer to a scientific question and is an important part of pi hypothesis is statement that can be proved or disproved as a result of experimentation BIU X² X₂ tutor ASK AN EXPERT 7 Paraphrasing Tool | QuillBo Ix CONTINUE study resources LIVE CHAT ((( Home Paste Page 1 of 2 OOO AutoSave OFF Insert Draw Design Layout X A A 000 Calibri (Bo... B I U Anti-HSV IgG Ab (μµg/ml) 000 V 12 V ✓ ab x₂ x² 10³ 10² 10¹ - 10⁰ 378 words QX Primary infection e 12 References Aa ✓ AA Mailings >> Tell me 3 4 5 Secondary infection X Figure 1 Focus WC7140 - Co... - Saved to my Mac Paragraph V A Q Styles Dictate V Wild-type C3 6 7 8 Weeks post- vaccination Sun 14 Aug 10:35 O Share Editor Comments + 321%
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