If acetyl-CoA is labeled with 14C at its methyl group, how many rounds of the cycle are required before 14CO2 is released? write out the whole pathway until 14CO2 is released.

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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2. If acetyl-CoA is labeled with 14C at its methyl group, how many

rounds of the cycle are required before 14CO2 is released?

write out the whole pathway until 14CO2 is released.

Expert Solution
Labelling of methyl group carbon

Let us label the methyl group of acetyl-CoA with 14-C (with a *)

Biochemistry homework question answer, step 1, image 1

These two carbons (one labelled with 14C, and the other carboxyl carbon) enter the citric acid cycle 

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