2. Draw the reactions catabolizing the amino acid valine into isobutryl-CoA, specifically onetransamination reaction (for which you do not need to show the mechanism) and one dehydrogenationreaction (which is analogous to the pyruvate dehydrogenase reaction mechanism, and for which youneed to show the mechanism using arrow pushing and including the relevant cofactors). Note: Beyondthe importance of these reactions for human health, this pathway is used industrially in the productionof isobutanol, an important biofuel.NH3SCOAvalineisobutyryl-CoA

Answered: Image /qna-images/answer/9bb87e63-7e45-42b9-9d69-8de540c3f09d.jpg

Answered: 2. Draw the reactions catabolizing the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

36. In the conversion of pyruvate to acetyl CoA, - an acetyl group is transferred to Coenzyme A to produce acetyl CoA. - only one pyruvate molecule loses one carbon atom with the release of carbon dioxide. - the succinate dehydrogenase complex requires four coenzymes. - electrons are transferred to NADH to produce NAD*.
9. The equation below depicts the first step of the citric acid cycle. H0 CoA-SH CH-C + 0=C-CO0 HO C-COO citrate s-COA ČH2-COO synthase ČH2 -CO0 Citrate Acetyl-CoA Oxaloacetate AG" = -32.2 kJ/mol a) Explain the chemical conversions that take place during this step. b) Why is this reaction energetically favorable? Explain.
Fill in the gaps (type your answers in all capital letters): Lactate fermentation is an important pathway, allowing the body to regenerate the co-factor in the absence of (molecule). During the process of cellular respiration, the enzyme converts pyruvate to acetyl-coA using five co-factors, including |(name one). Acetyl-CoA is a substrate of the ТСА сycle, where tior one acetyl-CoA one of the TCA cycle produces molecules of and 1 molecule of that function as electron carriers.
Answer should be 107 ATP. Can u help me to explain to me, please? I stuggled.
[References) Which of the following statements explains why acetyl-CoA Iis considered the central molecule of metabolism? (Select all that apply.) O The addition of acetyl-CoA to compounds stabilises them. Acetyl-CoA contains a thioester bond that makes it one of the high energy compounds in metabolic pathways. O Acetyl-CoA is an inhibitor that plays a central role in regulating metabolic pathways. O Acetyl-CoA feeds directly into the citric acid cycle. U None of the above.
2. Consider a preparation that contains all of the enzymes and cofactors needed for fatty acid biosynthesis from added malonyl-CoA and acetyl- COA. a. If [2-H) acetyl-CoA (labeled with deuterium) H-c-C-COA and an excess of unlabeled malonyl-CoA are added as substrates, how many deuterium atoms are incorporated into each palmitate? What are their locations in the palmitate structure? (Draw an expanded structural formula for palmitate showing the locations of the deuterium atoms (as drawn in acetyl-CoA above). Explain your answer.
Discuss the metabolic control for HMG CoA reductase synthesis and activity
1. What are the numbers of carbon atoms derived from the first acetyl-CoA that binds to fatty acid synthase complex in palmitate, the end product of the pathway? For the answer: a) name the initial substrates for fatty acid synthesis and their source; b) draw the reactions of the first spiral of fatty acid synthesis; b) mark the carbon atoms (*) derived from the first acetyl-CoA in the product of the first spiral of fatty acid synthesis; c) answer the question of the problem.
L What is the difference between the type of oxidation catalyzed by acyl-CoA dehydrogenase and that catalyzed by b-hydroxyCoA dehydrogenase
2. A 4-year-old girl was diagnosed with thiamine deficiency and the symptoms include tachycardia, vomiting, convulsions. Laboratory examinations reveal high levels of pyruvate, lactate and a-ketoglutarate. Explain which coenzyme is formed from vitamin B, and its role in oxidative decarboxylation of pyruvate. For that: a) describe the structure of pyruvate dehydrogenase complex (PDH) and the cofactors that it requires; b) discuss the symptoms which are connected with the thiamine deficiency and its effects on PDH and a-ketoglutarate dehydrogenase complex; c) explain the changes in the levels of mentioned metabolites in the blood; d) name the deseribed discase,
3. How is acetyl coA carboxylase being regulated?
38. The shown reaction is one of the four repeating steps during fatty acid biosynthesis. Which of the following statements is correct? 유 CH3-C-CH₂-C-S-ACP A B OH 유 CH3-C-CH₂-C-5-ACP → A. The small molecule in box A is NADPH + H* B. It is the second reduction reaction during fatty acid biosynthesis C. Both A and B D. Neither A nor B

SEE MORE QUESTIONS

Recommended textbooks for you

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781319114671

Author:

Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:

W. H. Freeman

Lehninger Principles of Biochemistry

Biochemistry

ISBN:

9781464126116

Author:

David L. Nelson, Michael M. Cox

Publisher:

W. H. Freeman

Fundamentals of Biochemistry: Life at the Molecul…

Biochemistry

ISBN:

9781118918401

Author:

Donald Voet, Judith G. Voet, Charlotte W. Pratt

Publisher:

WILEY

Biochemistry

ISBN:

9781305961135

Author:

Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal

Publisher:

Cengage Learning

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Fundamentals of General, Organic, and Biological …

Biochemistry

ISBN:

9780134015187

Author:

John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson

Publisher:

PEARSON

SEE MORE TEXTBOOKS

2. Draw the reactions catabolizing the amino acid valine into isobutryl-CoA, specifically one transamination reaction (for which you do not need to show the mechanism) and one dehydrogenation reaction (which is analogous to the pyruvate dehvdrogenase reaction mechanism, and for which vou